Inhaled medicines: past, present, and future

S Anderson, P Atkins, P Bäckman, D Cipolla… - Pharmacological …, 2022 - ASPET
The purpose of this review is to summarize essential pharmacological, pharmaceutical, and
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …

[HTML][HTML] Dry powder for pulmonary delivery: A comprehensive review

B Chaurasiya, YY Zhao - Pharmaceutics, 2021 - mdpi.com
The pulmonary route has long been used for drug administration for both local and systemic
treatment. It possesses several advantages, which can be categorized into physiological, ie …

Inhaled therapy in respiratory disease: the complex interplay of pulmonary kinetic processes

JM Borghardt, C Kloft, A Sharma - Canadian respiratory journal, 2018 - Wiley Online Library
The inhalation route is frequently used to administer drugs for the management of
respiratory diseases such as asthma or chronic obstructive pulmonary disease. Compared …

Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for pulmonary application: a review of the state of the art

S Weber, A Zimmer, J Pardeike - European Journal of Pharmaceutics and …, 2014 - Elsevier
Drug delivery by inhalation is a noninvasive means of administration that has following
advantages for local treatment for airway diseases: reaching the epithelium directly …

Dry powder inhalation: past, present and future

AH de Boer, P Hagedoorn, M Hoppentocht… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Early dry powder inhalers (DPIs) were designed for low drug doses in asthma
and COPD therapy. Nearly all concepts contained carrier-based formulations and lacked …

What the pulmonary specialist should know about the new inhalation therapies

BL Laube, HM Janssens, FHC de Jongh… - 2011 - Eur Respiratory Soc
A collaboration of multidisciplinary experts on the delivery of pharmaceutical aerosols was
facilitated by the European Respiratory Society (ERS) and the International Society for …

[HTML][HTML] Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines

Y Guo, H Bera, C Shi, L Zhang, D Cun… - Acta Pharmaceutica Sinica …, 2021 - Elsevier
Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

Delivery strategies for sustained drug release in the lungs

C Loira-Pastoriza, J Todoroff, R Vanbever - Advanced drug delivery reviews, 2014 - Elsevier
Drug delivery to the lungs by inhalation offers a targeted drug therapy for respiratory
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …

Choosing the right inhaler for your asthma or COPD patient

OS Usmani - Therapeutics and clinical risk management, 2019 - Taylor & Francis
Appropriate selection and correct use of inhalation devices is an integral component in the
management of asthma and chronic obstructive pulmonary disease (COPD). It is well known …