Machine learning in surface plasmon resonance for environmental monitoring

M Mohseni-Dargah, Z Falahati, B Dabirmanesh… - Artificial intelligence and …, 2022 - Elsevier
Biosensors are being used for diverse purposes, including food safety, biological studies,
drug screening, medical diagnosis, and environmental sensing. They have numerous …

DNA-based molecular recognition system for lactoferrin biosensing

A Paziewska-Nowak, M Urbanowicz… - International Journal of …, 2023 - Elsevier
The paper describes the development of a novel DNA oligonucleotide-based affinity
bioreceptor that binds to lactoferrin, a glycoprotein-type immunomodulator. The research …

A monoamine oxidase B inhibitor ethyl ferulate suppresses microglia-mediated neuroinflammation and alleviates ischemic brain injury

X Zou, S Gao, J Li, C Li, C Wu, X Cao, S Xia… - Frontiers in …, 2022 - frontiersin.org
Microglia are the resident macrophages in the brain, which play a critical role in post-stroke
neuroinflammation. Accordingly, targeting neuroinflammation could be a promising strategy …

Label-free impedimetric biosensor based on a novel DNA-type receptor for selective determination of lactoferrin in human saliva

A Paziewska-Nowak, M Urbanowicz… - Sensors and Actuators B …, 2024 - Elsevier
We propose a new impedimetric biosensor utilizing a unique H 2 N-(CH 2) 6-
5'[TAGAGGATCAAA-AAA] 4 TAGAGGATCAAA3'ds DNA oligonucleotide as a biorecognition …

Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo

JJ Tonge, SV Notley, MJ Dunning… - Scientific Reports, 2022 - nature.com
Infantile fibrosarcoma is a rare childhood tumour that originates in the fibrous connective
tissue of the long bones for which there is an urgent need to identify novel therapeutic …

Use of Surface Plasmon Resonance Technique for Studies of Inter-domain Interactions in Ion Channels

PB Tiwari, P Kamgar-Dayhoff, P Tiwari… - … Channels: Methods and …, 2024 - Springer
Ion channels are transmembrane proteins essential for cellular functions and are important
drug targets. Surface plasmon resonance (SPR) is a powerful technique for investigating …

[HTML][HTML] Validation of plasmonic-based biosensors for rapid and in depth characterization of monoclonal antibodies directed against rabbit haemorrhagic and foot-and …

C Urbinati, G Pezzoni, P Cavadini, V Di Giovanni… - Methods, 2025 - Elsevier
Abstract ELISA and RT-PCR represent the standard tools for the sensitive identification of
viruses in biological samples, but they lack the capacity to finely characterize the binding of …

The Type IV pilus secretin BfpB: structural analysis and binding interactions

JI Little - 2023 - scholarscompass.vcu.edu
Enteropathogenic Escherichia coli (EPEC) causes severe diarrhea in young children. The
type IV pilus (T4P) of EPEC, known as the bundle-forming pilus (BFP), plays an important …

Validation of plasmonic-based biosensors for rapid and sensitive detection of rabbit hemorrhagic and foot-and-mouth disease viruses in biological samples

C Urbinati, V Di Giovanni, G Pezzoni, L Capucci… - bioRxiv, 2024 - biorxiv.org
Biosensing technologies and monoclonal antibodies (MAbs) are gaining increasing
importance as powerful tools in the field of virology. Surface plasmon resonance (SPR) is an …

Fragment-Based Drug Design in Lead Discovery

AM Oliveira, M Rudrapal - CADD and Informatics in Drug Discovery, 2023 - Springer
This chapter focuses on the main new drug development strategies using the fragment-
based drug design (FBDD) approach and its relationship with high-throughput screening …