Molecular pathways of nonalcoholic fatty liver disease development and progression

F Bessone, MV Razori, MG Roma - Cellular and Molecular Life Sciences, 2019 - Springer
Nonalcoholic fatty liver disease (NAFLD) is a main hepatic manifestation of metabolic
syndrome. It represents a wide spectrum of histopathological abnormalities ranging from …

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement

SM Grundy, JI Cleeman, SR Daniels, KA Donato… - Circulation, 2005 - Am Heart Assoc
strongly with insulin resistance. Excess upper body fat can accumulate either
intraperitoneally (visceral fat) or subcutaneously. Many investigators claim that excess …

[HTML][HTML] Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: a systematic review

C Thoma, CP Day, MI Trenell - Journal of hepatology, 2012 - Elsevier
Non-alcoholic fatty liver disease is a serious and growing clinical problem. Despite lifestyle
modification, ie diet and physical activity, being the recommended therapy, there are …

Insulin resistance in nonalcoholic fatty liver disease

E Bugianesi, S Moscatiello… - Current …, 2010 - ingentaconnect.com
Nonalcoholic fatty liver disease (NAFLD) refers to a spectrum of liver damage ranging from
simple steatosis to nonalcoholic steatohepatitis (NASH), advanced fibrosis and cirrhosis …

Predictive value of ALT levels for non‐alcoholic steatohepatitis (NASH) and advanced fibrosis in non‐alcoholic fatty liver disease (NAFLD)

S Verma, D Jensen, J Hart, SR Mohanty - Liver International, 2013 - Wiley Online Library
Background Non‐alcoholic fatty liver disease (NAFLD) patients with elevated serum alanine
aminotransferase (ALT) generally undergo a liver biopsy to evaluate for possible non …

Overproduction of very low–density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome

M Adiels, SO Olofsson, MR Taskinen… - … , and vascular biology, 2008 - Am Heart Assoc
Insulin resistance is a key feature of the metabolic syndrome and often progresses to type 2
diabetes. Both insulin resistance and type 2 diabetes are characterized by dyslipidemia …

The epidemiology of nonalcoholic fatty liver disease: a global perspective

M Lazo, JM Clark - Seminars in liver disease, 2008 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized cause of liver
disease in the United States and worldwide. With obesity being an important risk factor …

[PDF][PDF] Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: a role for insulin resistance and diabetes

AL Fracanzani, L Valenti, E Bugianesi… - …, 2008 - Wiley Online Library
It is uncertain whether patients with nonalcoholic fatty liver disease (NAFLD) and normal
alanine aminotransferase (ALT) have a milder disease and should undergo liver biopsy. We …

Meta‐analysis: vitamin D and non‐alcoholic fatty liver disease

M Eliades, E Spyrou, N Agrawal, M Lazo… - Alimentary …, 2013 - Wiley Online Library
Background Non‐alcoholic fatty liver disease (NAFLD) is a highly prevalent condition.
Emerging evidence suggests that vitamin D may play a role in the pathogenesis of NAFLD …

[HTML][HTML] Nutrition and physical activity in NAFLD: an overview of the epidemiological evidence

S Zelber-Sagi, V Ratziu, R Oren - World journal of …, 2011 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) has been recognized as a major health burden.
The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity …