Breathing life into engineered tissues using oxygen-releasing biomaterials

S Suvarnapathaki, X Wu, D Lantigua, MA Nguyen… - NPG Asia …, 2019 - nature.com
Abstract Engineering three-dimensional (3D) tissues in clinically relevant sizes have
demonstrated to be an effective solution to bridge the gap between organ demand and the …

Polymers for tissue engineering, medical devices, and regenerative medicine. Concise general review of recent studies

J Jagur‐Grodzinski - Polymers for advanced technologies, 2006 - Wiley Online Library
Recently investigated applications of polymeric materials for tissue engineering,
regenerative medicine, implants, stents, and medical devices are described in the present …

Gelatin‐methacrylamide hydrogels as potential biomaterials for fabrication of tissue‐engineered cartilage constructs

W Schuurman, PA Levett, MW Pot… - Macromolecular …, 2013 - Wiley Online Library
Gelatin‐methacrylamide (gelMA) hydrogels are shown to support chondrocyte viability and
differentiation and give wide ranging mechanical properties depending on several cross …

Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates

IS Kinstlinger, SH Saxton, GA Calderon… - Nature biomedical …, 2020 - nature.com
Sacrificial templates for patterning perfusable vascular networks in engineered tissues have
been constrained in architectural complexity, owing to the limitations of extrusion-based 3D …

[HTML][HTML] Symbiotic photosynthetic oxygenation within 3D-bioprinted vascularized tissues

S Maharjan, J Alva, C Cámara, AG Rubio… - Matter, 2021 - cell.com
In this study, we present the photosynthetic oxygen (O 2) supply to mammalian cells within a
volumetric extracellular matrix-like construct, whereby a three-dimensional (3D)-bioprinted …

Oxygen gradients correlate with cell density and cell viability in engineered cardiac tissue

M Radisic, J Malda, E Epping, W Geng… - Biotechnology and …, 2006 - Wiley Online Library
For clinical utility, cardiac grafts should be thick and compact, and contain physiologic
density of metabolically active, differentiated cells. This involves the need to control the …

Oxygen generating scaffolds for enhancing engineered tissue survival

SH Oh, CL Ward, A Atala, JJ Yoo, BS Harrison - Biomaterials, 2009 - Elsevier
One of the continued challenges in engineering clinically applicable tissues is the
establishment of vascularization upon implantation in vivo. Although the effectiveness of an …

Osteochondral tissue engineering

I Martin, S Miot, A Barbero, M Jakob, D Wendt - Journal of biomechanics, 2007 - Elsevier
Osteochondral defects (ie, defects which affect both the articular cartilage and underlying
subchondral bone) are often associated with mechanical instability of the joint, and therefore …

The Roles of Hypoxia in the In Vitro Engineering of Tissues

J Malda, TJ Klein, Z Upton - Tissue engineering, 2007 - liebertpub.com
Oxygen is a potent modulator of cell function and wound repair in vivo. The lack of oxygen
(hypoxia) can create a potentially lethal environment and limit cellular respiration and …

Oxygen-releasing antioxidant cryogel scaffolds with sustained oxygen delivery for tissue engineering applications

PA Shiekh, A Singh, A Kumar - ACS applied materials & interfaces, 2018 - ACS Publications
With the advancement in biomaterial sciences, tissue-engineered scaffolds are developing
as a promising strategy for the regeneration of damaged tissues. However, only a few of …