Portal vein tumor thrombosis in hepatocellular carcinoma: molecular mechanism and therapy

XH Zhou, JR Li, TH Zheng, H Chen, C Cai… - Clinical & Experimental …, 2023 - Springer
Portal vein tumor thrombosis (PVTT), a common complication of advanced hepatocellular
carcinoma (HCC), remains the bottleneck of the treatments. Liver cancer cells potentially …

Comparative assessment of Fgf's diverse roles in inner ear development: A zebrafish perspective

BB Riley - Developmental Dynamics, 2021 - Wiley Online Library
Progress in understanding mechanisms of inner ear development has been remarkably
rapid in recent years. The research community has benefited from the availability of several …

[HTML][HTML] sox2 and sox3 Play unique roles in development of hair cells and neurons in the zebrafish inner ear

Y Gou, S Vemaraju, EM Sweet, HJ Kwon… - Developmental biology, 2018 - Elsevier
Formation of neural and sensory progenitors in the inner ear requires Sox2 in mammals,
and in other species is thought to rely on both Sox2 and Sox3. How Sox2 and/or Sox3 …

Blast-induced hearing impairment in rats is associated with structural and molecular changes of the inner ear

Y Wang, RT Urioste, Y Wei, DM Wilder, P Arun… - Scientific reports, 2020 - nature.com
Auditory dysfunction is the most prevalent injury associated with blast overpressure
exposure (BOP) in Warfighters and civilians, yet little is known about the underlying …

Pax2a, Sp5a and Sp5l act downstream of Fgf and Wnt to coordinate sensory-neural patterning in the inner ear

AL Tan, S Mohanty, J Guo, AC Lekven, BB Riley - Developmental Biology, 2022 - Elsevier
In zebrafish, sensory epithelia and neuroblasts of the inner ear form simultaneously in
abutting medial and lateral domains, respectively, in the floor of the otic vesicle. Previous …

A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse

B Ulmer, M Tingler, S Kurz, M Maerker, P Andre… - Scientific reports, 2017 - nature.com
Goosecoid (Gsc) expression marks the primary embryonic organizer in vertebrates and
beyond. While functions have been assigned during later embryogenesis, the role of Gsc in …

Transcriptomic profiling of Hydra magnipapillata after exposure to naproxen

A Yamindago, N Lee, S Woo, S Yum - Environmental toxicology and …, 2019 - Elsevier
The extensive use in humans and animals of nonsteroidal anti-inflammatory drugs (NSAIDs)
increases their possible impact on aquatic organisms. In the present study, we investigated …

Single-cell RNA sequencing of mid-to-late stage spider embryos: new insights into spider development

BI Medina-Jiménez, GE Budd, R Janssen - BMC genomics, 2024 - Springer
Background The common house spider Parasteatoda tepidariorum represents an emerging
new model organism of arthropod evolutionary and developmental (EvoDevo) studies …

The Warburg Effect and lactate signaling augment Fgf-MAPK to promote sensory-neural development in the otic vesicle

H Kantarci, Y Gou, BB Riley - Elife, 2020 - elifesciences.org
Recent studies indicate that many developing tissues modify glycolysis to favor lactate
synthesis (Agathocleous et al., 2012; Bulusu et al., 2017; Gu et al., 2016; Oginuma et al …

Effects of miR-181a-5p abnormal expression on zebrafish (Danio rerio) vascular development following triclosan exposure

Y Ma, L Zang, D Wang, J Jiang, C Wang, X Wang… - Chemosphere, 2019 - Elsevier
Triclosan (TCS), one of the important bactericides, is widely used in personal care products,
and its chronic exposure leads to severe toxic effects on the growth and development of …