[HTML][HTML] Nanoparticles and cytokine response
M Nasrullah, DN Meenakshi Sundaram… - … in Bioengineering and …, 2023 - frontiersin.org
Synthetic nanoparticles (NPs) are non-viral equivalents of viral gene delivery systems that
are actively explored to deliver a spectrum of nucleic acids for diverse range of therapies …
are actively explored to deliver a spectrum of nucleic acids for diverse range of therapies …
Mesenchymal stromal cells derived from dental tissues: immunomodulatory properties and clinical potential
LI Poblano-Pérez, ME Castro-Manrreza… - International Journal of …, 2024 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells located in different areas of
the human body. The oral cavity is considered a potential source of MSCs because they …
the human body. The oral cavity is considered a potential source of MSCs because they …
The effect of TLR3 priming conditions on MSC immunosuppressive properties
T Tolstova, E Dotsenko, P Kozhin, S Novikova… - Stem Cell Research & …, 2023 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) have regenerative and
immunomodulatory properties, making them suitable for cell therapy. Toll-like receptors …
immunomodulatory properties, making them suitable for cell therapy. Toll-like receptors …
hPMSCs Regulate the Level of TNF-α and IL-10 in Th1 Cells and Improve Hepatic Injury in a GVHD Mouse Model via CD73/ADO/Fyn/Nrf2 Axis
H Zhang, K Han, H Li, J Zhang, Y Zhao, Y Wu, B Wang… - Inflammation, 2024 - Springer
Mesenchymal stem cells (MSCs) ameliorate graft-versus-host disease (GVHD)-induced
tissue damage by exerting immunosuppressive effects. However, the related mechanism …
tissue damage by exerting immunosuppressive effects. However, the related mechanism …
Human umbilical cord derived mesenchymal stem cells overexpressing HO‐1 attenuate neural injury and enhance functional recovery by inhibiting inflammation in …
Y Yang, Q Liu, S Deng, Q Shao, L Peng… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims The current evidence demonstrates that mesenchymal stem cells (MSCs) hold
therapeutic potential for ischemic stroke. However, it remains unclear how changes in the …
therapeutic potential for ischemic stroke. However, it remains unclear how changes in the …
Innovative nonviral gene delivery strategies for engineering human mesenchymal stem cell phenotypes toward clinical applications
A Hamann, AK Pannier - Current opinion in biotechnology, 2022 - Elsevier
Highlights•hMSCs have been registered in almost 1,000 clinical trials, but no FDA
approvals.•Nonviral gene delivery could enhance hMSCs, but is inefficient.•hMSC …
approvals.•Nonviral gene delivery could enhance hMSCs, but is inefficient.•hMSC …
Effects of organic trace minerals chelated with oligosaccharides on growth performance, blood parameters, slaughter performance and meat quality in sheep
R Zhang, M Wei, J Zhou, Z Yang, M Xiao… - Frontiers in Veterinary …, 2024 - frontiersin.org
The present study assessed the effects of oligosaccharide-chelated organic trace minerals
(OTM) on the growth performance, digestive enzyme activity, blood parameters, slaughter …
(OTM) on the growth performance, digestive enzyme activity, blood parameters, slaughter …
IL-10RA governor the expression of IDO in the instruction of lymphocyte immunity
TS Tai, DW Hsu, YS Yang, CY Tsai, JW Shi… - British Journal of …, 2024 - nature.com
Abstract Background Indoleamine 2, 3-dioxygenase (IDO) impairs anti-pathogen and anti-
tumour immunity. Mesenchymal stem cells (MSCs) modulate immunity via IDO but also …
tumour immunity. Mesenchymal stem cells (MSCs) modulate immunity via IDO but also …
Oral cancer cells release vesicles that cause pain
ZA Dubeykovskaya, NH Tu, PDR Garcia… - Advanced …, 2022 - Wiley Online Library
Oral cancer pain is attributed to the release from cancers of mediators that sensitize and
activate sensory neurons. Intraplantar injection of conditioned media (CM) from human …
activate sensory neurons. Intraplantar injection of conditioned media (CM) from human …
In Vitro Transcribed mRNA Immunogenicity Induces Chemokine‐Mediated Lymphocyte Recruitment and Can Be Gradually Tailored by Uridine Modification
NM Drzeniek, N Kahwaji, S Picht… - Advanced …, 2024 - Wiley Online Library
Abstract Beyond SARS‐CoV2 vaccines, mRNA drugs are being explored to overcome
today's greatest healthcare burdens, including cancer and cardiovascular disease. Synthetic …
today's greatest healthcare burdens, including cancer and cardiovascular disease. Synthetic …