In severe asthma, symptoms are unstable despite intensive treatment based on high doses
of inhaled corticosteroids and on-demand use of oral corticosteroids. Although, recently …

Osteoarthritis (OA), a chronic degenerative joint disease, is the most common form of
arthritis. OA occurs when the protective cartilage that cushions the ends of bones gradually …

Functional loss of the motor protein myosin Vb (MYO5B) induces various defects in intestinal
epithelial function and causes a congenital diarrheal disorder, namely, microvillus inclusion …

Hypoxia-induced radioresistance reduces the efficacy of radiotherapy for solid
malignancies, including non-small cell lung cancer (NSCLC). Cellular hypoxia can confer …

Lysophosphatidic acids (LPAs) evoke nociception and itch in mice and humans. In this
study, we assessed the signaling paths. Hydroxychloroquine was injected intradermally to …

Cancer is a complex disease that can also affect the younger population; however, it is
responsible for a relatively high mortality rate of children and youth, especially in low-and …

Extracellular lysophospholipids (lysophosphatidic acid, lysophosphatidylcholine,
sphingosine 1-phosphate, etc.), which are synthesized from phospholipids in the cell …

Despite extensive studies on endogenous heart regeneration within the past 20 years, the
players involved in initiating early regeneration events are far from clear. Here, we assessed …

Introduction The prognosis of multiple myeloma (MM) continues to improve. Recent progress
in therapies, using immunomodulatory drugs (IMiDs), proteasome inhibitors (PIs), and anti …

Functional loss of the motor protein, Myosin Vb (MYO5B), induces various defects in
intestinal epithelial function and causes a congenital diarrheal disorder, microvillus inclusion …