Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …

Artificial intelligence (AI), and, in particular, deep learning as a subcategory of AI, provides
opportunities for the discovery and development of innovative drugs. Various machine …

Background: Determining drug–disease associations is an integral part in the process of
drug development. However, the identification of drug–disease associations through wet …

Given the high attrition rates, substantial costs and slow pace of new drug discovery and
development, repurposing of'old'drugs to treat both common and rare diseases is …

Drug repurposing holds the potential to bring medications with known safety profiles to new
patient populations. Numerous examples exist for the identification of new indications for …

Computational drug repositioning or repurposing is a promising and efficient tool for
discovering new uses from existing drugs and holds the great potential for precision …

Drug-drug interaction (DDI) is an important topic for public health and thus attracts attention
from both academia and industry. Here we hypothesize that clinical side effects (SEs) …

Adverse drug events remain a leading cause of morbidity and mortality around the world.
Many adverse events are not detected during clinical trials before a drug receives approval …

Background Drug-disease associations provide important information for the drug discovery.
Wet experiments that identify drug-disease associations are time-consuming and expensive …

Data in the biological, chemical, and clinical domains are accumulating at ever‐increasing
rates and have the potential to accelerate and inform drug development in new ways …