The dawning era of oral thin films for nutraceutical delivery: From laboratory to clinic

N Khan, SS Dogra, A Saneja - Biotechnology Advances, 2024 - Elsevier
Oral thin films (OTFs) are innovative dosage forms that have gained tremendous attention for
the delivery of nutraceuticals. They are ultra-thin, flexible sheets that can be easily placed on …

Orodispersible films—Current state of the art, limitations, advances and future perspectives

J Ferlak, W Guzenda, T Osmałek - Pharmaceutics, 2023 - mdpi.com
Orodispersible Films (ODFs) are drug delivery systems manufactured with a wide range of
methods on a big scale or for customized medicines and small-scale pharmacy. Both ODFs …

Orodispersible films: current innovations and emerging trends

S Jacob, SHS Boddu, R Bhandare, SS Ahmad, AB Nair - Pharmaceutics, 2023 - mdpi.com
Orodispersible films (ODFs) are thin, mechanically strong, and flexible polymeric films that
are designed to dissolve or disintegrate rapidly in the oral cavity for local and/or systemic …

Optimized L-SNEDDS and spray-dried S-SNEDDS using a linked QbD-DM3 rational design for model compound ketoprofen

VD Patel, V Rathod, RV Haware, WC Stagner - International Journal of …, 2023 - Elsevier
A QbD-DM 3 strategy was used to design ketoprofen (KTF) optimized liquid (L-SNEDDS)
and solid self-nanoemulsifying drug delivery systems (S-SNEDDS). Principal component …

Effect of chemical penetration enhancers on the transdermal delivery of olanzapine in human skin in vitro

A Virani, N Dholaria, H Mohd, N Albayati… - AAPS Open, 2024 - Springer
This research study involves the development of an olanzapine (OLZ) formulation using
various chemical penetration enhancers (CPEs) for transdermal delivery. The aim of this …

Formulation and characterization of tadalafil-loaded orodispersible films with enhanced dissolution rate and membrane permeability

ZL Zhao, D Peng, X Liu, XC Li, LJ Lan, XH Wu… - Journal of Drug Delivery …, 2023 - Elsevier
The low solubility of tadalafil (TDF) normally retards the dissolution rate and permeability of
the drug in oral mucosa and gastrointestinal tract. The aim of this study was to optimize and …

Strategizing spray drying process optimization for the manufacture of redispersible indomethacin nanoparticles using quality-by-design principles

V Rathod, B Gajera, A Pinninti, IA Mohammed… - AAPS …, 2023 - Springer
The present study adopted a Quality by Design (QbD) approach to spray dry indomethacin
nanosuspension (IMC-NS) consisting of HPC-SL, poloxamer 407, and lactose monohydrate …

Buccal films: an assessment of protuberant features, manufacturing contemplations, formulation techniques & characterization strictures

S Faheem, H Hameed, M Zaman… - … Journal of Polymeric …, 2024 - Taylor & Francis
The delivery via buccal route of small molecules as well as large molecules has been a
catching administration route and it was extensively studied over the last few periods. Such …

[HTML][HTML] Oral fast dissolving films for co-administration of breviscapine and matrine: Formulation optimization and in vitro characterization

H Yin, W Jin, J Wang, J Ke, W Zhang, C Liu… - Journal of Drug Delivery …, 2024 - Elsevier
Oral fast dissolving films (OFDFs) are popular dosage forms for enhanced oral absorption of
active ingredients without experiencing gastrointestinal interference or first-pass …

Design of Experiments-Driven Optimization of Spray Drying for Amorphous Clotrimazole Nanosuspension

B Gajera, H Shah, B Parekh, V Rathod, M Tilala… - AAPS …, 2024 - Springer
This study employed a Quality by Design (QbD) approach to spray dry
amorphousclotrimazole nanosuspension (CLT-NS) consisting of Soluplus® and …