Cardioprotective potential of vanillic acid

B Yalameha, HR Nejabati… - Clinical and Experimental …, 2023 - Wiley Online Library
Nowadays, cardiovascular diseases (CVDs) are a global threat to public health, accounting
for almost one‐third of all deaths worldwide. One of the key mechanistic pathways …

Protective effects of vanillic acid on autistic-like behaviors in a rat model of maternal separation stress: Behavioral, electrophysiological, molecular and …

M Farzan, M Farzan, H Amini-Khoei, M Shahrani… - International …, 2023 - Elsevier
Compounds derived from herbs exhibit a range of biological properties, including anti-
inflammatory, antioxidant, and neuroprotective properties. However, the exact mechanism of …

Neuroprotection impact of biochanin A against pentylenetetrazol-kindled mice: targeting NLRP3 inflammasome/TXNIP pathway and autophagy modulation

RM El-Sayed, MN Fawzy, HF Zaki… - International …, 2023 - Elsevier
Recurrent seizures characterize epilepsy, a complicated and multifaceted neurological
disease. Several neurological alterations, such as cell death and the growth of gorse fibers …

Vanillic acid abrogates cisplatin-induced ovotoxicity through activating Nrf2 pathway

A Mentese, S Demir, H Kucuk, E Yulug, NT Alemdar… - Tissue and Cell, 2023 - Elsevier
Although cisplatin (CDDP) is an effective anticancer agent, the ovotoxicity that can occur in
female patients limits its use. Oxidative stress (OS) and inflammation are known to contribute …

Amomum subulatum fruits protect against radiation-induced esophagitis by regulating antioxidant status and inflammatory responses

S Drishya, SS Dhanisha, P Raghukumar… - Food Research …, 2023 - Elsevier
Radiation esophagitis (RE) is an inimical event that requires proper management while
carrying out radiotherapy for thoracic cancers. The present study investigates the protective …

Underlying mechanisms behind the neuroprotective effect of vanillic acid against diabetes‐associated cognitive decline: An in vivo study in a rat model

S Ghaderi, P Gholipour, A Komaki… - Phytotherapy …, 2024 - Wiley Online Library
Hippocampal synaptic dysfunction, oxidative stress, neuroinflammation, and neuronal loss
play critical roles in the pathophysiology of diabetes‐associated cognitive decline (DACD) …

Amomum subulatum mitigates experimental thoracic radiation-induced lung injury by regulating antioxidant status and inflammatory responses

S Drishya, SS Dhanisha, P Raghukumar… - Food & function, 2023 - pubs.rsc.org
Radiation-induced lung injury (RILI) is one of the most prominent complications of thoracic
radiotherapy for which effective therapy is still lacking. This study investigates the …

Carboxylic Acids as Activators of NRF2: Antioxidant and Anti-inflammatory Effects

MC Egbujor - Medicinal Chemistry, 2024 - benthamdirect.com
The complex interaction between carboxylic acids and molecular signaling pathways,
particularly the nuclear factor erythroid 2-related factor 2 (NRF2) pathway, is of growing …

[HTML][HTML] Uncovering the protective potential of vanillic acid against traumatic brain injury-induced cognitive decline in male rats: Insights into underlying mechanisms

S Ghaderi, P Gholipour, S Safari, SM Sadati… - Biomedicine & …, 2024 - Elsevier
Traumatic brain injury (TBI) is a significant contributor to global mortality and disability, and
there is still no specific drug available to treat cognitive deficits in survivors. Vanillic acid …

A novel pathway phenotype of temporal lobe epilepsy and comorbid psychiatric disorders: results of precision nomothetic medicine

M Maes, DS Barbosa, AF Almulla, B Kanchanatawan - Antioxidants, 2022 - mdpi.com
No precision medicine models of temporal lobe epilepsy (TLE) and associated mental
comorbidities have been developed to date. This observational study aimed to develop a …