Pathophysiological mechanisms of liver injury in COVID‐19

AD Nardo, M Schneeweiss‐Gleixner… - Liver …, 2021 - Wiley Online Library
The recent outbreak of coronavirus disease 2019 (COVID‐19), caused by the Severe Acute
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) has resulted in a world‐wide …

Overview of immune response during SARS-CoV-2 infection: lessons from the past

VK Shah, P Firmal, A Alam, D Ganguly… - Frontiers in …, 2020 - frontiersin.org
After the 1918 flu pandemic, the world is again facing a similar situation. However, the
advancement in medical science has made it possible to identify that the novel infectious …

Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19

B Boras, RM Jones, BJ Anson, D Arenson… - Nature …, 2021 - nature.com
COVID-19 caused by the SARS-CoV-2 virus has become a global pandemic. 3CL protease
is a virally encoded protein that is essential across a broad spectrum of coronaviruses with …

Activation and evasion of type I interferon responses by SARS-CoV-2

X Lei, X Dong, R Ma, W Wang, X Xiao, Z Tian… - Nature …, 2020 - nature.com
The pandemic of COVID-19 has posed an unprecedented threat to global public health.
However, the interplay between the viral pathogen of COVID-19, SARS-CoV-2, and host …

[HTML][HTML] Structural basis of receptor recognition by SARS-CoV-2

J Shang, G Ye, K Shi, Y Wan, C Luo, H Aihara, Q Geng… - Nature, 2020 - nature.com
A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently
emerged and is rapidly spreading in humans, causing COVID-19 1, 2. A key to tackling this …

[HTML][HTML] Pulmonary pathology of ARDS in COVID-19: A pathological review for clinicians

SS Batah, AT Fabro - Respiratory medicine, 2021 - Elsevier
COVID-19 has quickly reached pandemic levels since it was first reported in December
2019. The virus responsible for the disease, named SARS-CoV-2, is enveloped positive …

Discovery of ketone-based covalent inhibitors of coronavirus 3CL proteases for the potential therapeutic treatment of COVID-19

RL Hoffman, RS Kania, MA Brothers… - Journal of medicinal …, 2020 - ACS Publications
The novel coronavirus disease COVID-19 that emerged in 2019 is caused by the virus
SARS CoV-2 and named for its close genetic similarity to SARS CoV-1 that caused severe …

Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus

Y Wan, J Shang, R Graham, RS Baric, F Li - Journal of virology, 2020 - Am Soc Microbiol
ABSTRACT Recently, a novel coronavirus (2019-nCoV) has emerged from Wuhan, China,
causing symptoms in humans similar to those caused by severe acute respiratory syndrome …

Quercetin and vitamin C: an experimental, synergistic therapy for the prevention and treatment of SARS-CoV-2 related disease (COVID-19)

RML Colunga Biancatelli, M Berrill… - Frontiers in …, 2020 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) represents an emergent
global threat which is straining worldwide healthcare capacity. As of May 27th, the disease …

The molecular virology of coronaviruses

E Hartenian, D Nandakumar, A Lari, M Ly… - Journal of Biological …, 2020 - ASBMB
Few human pathogens have been the focus of as much concentrated worldwide attention as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its …