Abstract Introduction 5-fluorouracil, folinic acid, irinotecan and oxaliplatin (FOLFIRINOX) is
promising in treating patients with pancreatic ductal adenocarcinoma. However, many …

Cryopreservation of whole blood is useful for DNA collection, and clinical and basic
research. Blood samples in ethylenediaminetetraacetic acid disodium salt (EDTA) tubes …

Each cell controls when and how its genes must be expressed for proper function. Every
function in a cell is driven by signaling molecules through various regulatory cascades …

Preeclampsia is a severe placenta-related pregnancy disorder that is generally divided into
two subtypes named early-onset preeclampsia (onset< 34 weeks of gestation), and late …

Fibromyalgia syndrome (FMS) is a heterogeneous chronic pain syndrome characterized by
musculoskeletal pain and other key co-morbidities including fatigue and a depressed mood …

The prognosis of pediatric central nervous system (CNS) malignancies remains dismal due
to limited treatment options, resulting in high mortality rates and long-term morbidities …

Background Meibomian gland dysfunction (MGD) is one of the most common conditions in
ophthalmic practice and the most frequent cause of evaporative dry eye disease (DED) …

Introduction Atherosclerosis is one of the main reasons for adult mortality in advanced
populations and countries with high stress levels. Klotho family are single-pass trans …

Background: Atherosclerosis represents one of the major causes of morbidity in children
with β-thalassemia major (β-TM). Aim: This study was designed to investigate SIRT1-FOXO1 …

Peripheral blood RNA profiling, which can reveal systemic changes in gene expression and
immune responses to disease onset and progression, is a powerful tool for diagnosis and …