R Biselli, R Nisini, F Lista, A Autore, M Lastilla… - Biomedicines, 2022 - mdpi.com
The environmental conditions generated by war and characterized by poverty, undernutrition, stress, difficult access to safe water and food as well as lack of environmental …
ST Smiley - Immunological reviews, 2008 - Wiley Online Library
Yersinia pestis is one of the world's most virulent human pathogens. Inhalation of this Gram‐ negative bacterium causes pneumonic plague, a rapidly progressing and usually fatal …
Pneumonic plague is a highly virulent infectious disease with 100% mortality rate, and its causative organism Yersinia pestis poses a serious threat for deliberate use as a bioterror …
B Carrillo-Conde, E Schiltz, J Yu, FC Minion… - Acta biomaterialia, 2010 - Elsevier
The design of biodegradable polymeric delivery systems based on polyanhydrides that would provide for improved structural integrity of Yersinia pestis antigens was the main goal …
CE Chandler, EM Harberts… - Proceedings of the …, 2020 - National Acad Sciences
Immune evasion through membrane remodeling is a hallmark of Yersinia pestis pathogenesis. Yersinia remodels its membrane during its life cycle as it alternates between …
DA Wagner, SM Kelly, AC Petersen, N Peroutka-Bigus… - Acta biomaterialia, 2019 - Elsevier
Yersinia pestis, the causative agent of pneumonic plague, induces a highly lethal infection if left untreated. Currently, there is no FDA-approved vaccine against this pathogen; however …
R Rosario-Acevedo, SS Biryukov, JA Bozue, CK Cote - Biomedicines, 2021 - mdpi.com
Plague, caused by the bacterial pathogen Yersinia pestis, is a vector-borne disease that has caused millions of human deaths over several centuries. Presently, human plague infections …
In this study, we compare four different adjuvants, LT (R192G), CpG ODN, MPL® TDM, and alum, for their ability to affect the magnitude, distribution, and duration of antibody responses …
VA Feodorova, LN Pan'kina, EP Savostina… - Vaccine, 2007 - Elsevier
The lpxM mutant of the live vaccine Yersinia pestis EV NIIEG strain synthesising a less toxic penta-acylated lipopolysaccharide was found to be avirulent in mice and guinea pigs …