Obesity and the associated metabolic syndrome is considered a pandemic whose
prevalence is steadily increasing in many countries worldwide. It is a complex, dynamic, and …

Circadian rhythms at a central and peripheral level are operated by transcriptional/
translational feedback loops involving a set of genes called 'clock genes' that have been …

The many circadian clock genes buildup a network structure that controls physiological
processes such as sleep cycle, metabolism and hormone secretion. A close relationship …

The circadian clock (CC) is a daily system that regulates the oscillations of physiological
processes and can respond to the external environment in order to maintain internal …

Background T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological
malignancy, characterized by restricted cellular subsets with asymmetrically enriched …

Background: Recent research underscores a crucial connection between circadian rhythm
disruption and cancer promotion, highlighting an urgent need for attention. Objectives …

Background/Aim: Cryptochrome 1 (CRY1), a core circadian gene, modulates circadian
rhythm and carcinogenesis. Here, we investigated the role of CRY1 and its correlation with …

The PI3K/AKT pathway plays an important role in the development of osteosarcoma. RNF38
interferes with activation of the AKT pathway. Cryptochrome1 (CRY1) inhibits osteosarcoma …

ABSTRACT C1q/tumor necrosis factor-related protein 3 (CTRP3) has been demonstrated to
play a protective role in mice with severe acute pancreatitis (SAP). However, its clinical …

Abstract Aziz Sancar, Nobel Prize winning Turkish scientist, made several discoveries which
had a major impact on molecular sciences, particularly disciplines that focus on …