Gamma frequency oscillations are thought to provide a temporal structure for information
processing in the brain. They contribute to cognitive functions, such as memory formation …

The neuronal and synaptic organisation of the cerebral cortex appears exceedingly
complex, and the definition of a basic cortical circuit in terms of defined classes of cells and …

Type A γ-aminobutyric acid receptors (GABAARs) are pentameric ligand-gated chloride
channels that mediate fast inhibitory signalling in neural circuits, and can be modulated by …

The hippocampus is one of a group of remarkable structures embedded within the brain's
medial temporal lobe. Long known to be important for memory, it has been a prime focus of …

Hippocampal synaptic inhibition is mediated by distinct groups of inhibitory cells. Some
contact pyramidal cells perisomatically, while others terminate exclusively on their dendrites …

In the adult hippocampus and olfactory bulb, neural progenitor cells generate neurons that
functionally integrate into the existing circuits. To understand how neuronal differentiation …

The α5 subunit of the GABAA receptor is localized mainly to the hippocampus of the
mammalian brain. The significance of this rather distinct localization and the function of α5 …

A fragile balance between excitation and inhibition maintains the normal functioning of the
CNS. The dominant inhibitory neurotransmitter of the mammalian brain is GABA, which acts …

In the brain, highly connected and heterogeneous GABAergic cells are crucial in controling
the activity of neuronal networks. They accomplish this task by communicating through …

1. We have shown previously, with experimental and computer models, how a '40
Hz'(gamma) oscillation can arise in networks of hippocampal interneurones, involving …