Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Mercury (Hg) is a persistent bio-accumulative toxic metal with unique physicochemical
properties of public health concern since their natural and anthropogenic diffusions still …

Multiple abnormalities occur in the homeostasis of essential endogenous brain biometals in
age-related neurodegenerative disorders, Alzheimer's disease, Parkinson's disease …

Tannins, also known as plant polyphenols (PPs), are secondary metabolites widely existing
in higher plants and are a kind of natural renewable resource with wide distribution, variety …

In this review, primary attention is given to the antioxidant (and prooxidant) activity of
polyphenols arising from their interactions with iron both in vitro and in vivo. In addition, an …

The Metallothionein (MT) is a protein which has several interesting biological effects and
has been demonstrated increase focus on the role of MT in various biological systems in the …

Neurodegenerative diseases constitute a worldwide health problem. Metals like iron and
copper are essential for life, but they are also involved in several neurodegenerative …

Over-expression of mutant copper, zinc superoxide dismutase (SOD) in mice induces ALS
and has become the most widely used model of neurodegeneration. However, no …

The effect of redox metals such as iron and copper on multiple sclerosis and amyotrophic
lateral sclerosis has been intensively studied. However, the origin of these disorders …

The excitatory neurotransmission of the central nervous system (CNS) mainly involves
glutamate and its receptors, especially N-methyl-D-Aspartate receptors (NMDARs). These …