Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials

Y Zhu, T Zhao, M Liu, S Wang, S Liu, Y Yang, Y Yang… - Nano Today, 2022 - Elsevier
Rheumatoid arthritis (RA) causes a huge medical burden due to its high morbidity and
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …

[HTML][HTML] Polysaccharide-based nanomedicines for cancer immunotherapy: A review

Y Zeng, Y Xiang, R Sheng, H Tomás, J Rodrigues… - Bioactive Materials, 2021 - Elsevier
Cancer immunotherapy is an effective antitumor approach through activating immune
systems to eradicate tumors by immunotherapeutics. However, direct administration of …

[HTML][HTML] Nanoenzyme engineered neutrophil-derived exosomes attenuate joint injury in advanced rheumatoid arthritis via regulating inflammatory environment

L Zhang, Z Qin, H Sun, X Chen, J Dong, S Shen… - Bioactive materials, 2022 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovitis and
destruction of cartilage, promoted by sustained inflammation. However, current treatments …

Radicals scavenging MOFs enabling targeting delivery of siRNA for rheumatoid arthritis therapy

L Guo, S Zhong, P Liu, M Guo, J Ding, W Zhou - Small, 2022 - Wiley Online Library
Macrophages play essential roles in the progression of rheumatoid arthritis (RA), which are
polarized into the pro‐inflammatory M1 phenotype with significant oxidative stress and …

Bioinspired nanogels as cell-free DNA trapping and scavenging organelles for rheumatoid arthritis treatment

H Zhu, B Kong, J Che, Y Zhao… - Proceedings of the …, 2023 - National Acad Sciences
Excessive cell-free DNA (cfDNA) in the serum and synovium is considered a causative factor
of rheumatoid arthritis (RA). Thus, cfDNA scavenging by using cationic polymers has been …

Engineered Bio‐Heterojunction with Infection‐Primed H2S Liberation for Boosted Angiogenesis and Infectious Cutaneous Regeneration

Y Huang, Y Huang, Z Wang, S Yu, HM Johnson… - Small, 2023 - Wiley Online Library
Photodynamic therapy (PDT) acts as a powerful weapon against infectious diseases for its
enormous antimicrobial activity that quickly elicits storms of reactive oxygen species (ROS) …

Multifunctional Janus nanoplatform for efficiently synergistic theranostics of rheumatoid arthritis

Y Liu, L Chen, Z Chen, M Liu, X Li, Y Kou, MM Hou… - ACS …, 2023 - ACS Publications
Progress has been made in the application of nanomedicine in rheumatoid arthritis (RA)
treatment. However, the whole process of monitoring and treatment of RA remains a …

Succinate metabolism and its regulation of host-microbe interactions

Y Wei, X Ma, JC Zhao, XQ Wang, CQ Gao - Gut Microbes, 2023 - Taylor & Francis
Succinate is a circulating metabolite, and the relationship between abnormal changes in the
physiological concentration of succinate and inflammatory diseases caused by the …

Reactive oxygen species-based biomaterials for regenerative medicine and tissue engineering applications

M Shafiq, Y Chen, R Hashim, C He, X Mo… - … in Bioengineering and …, 2021 - frontiersin.org
Reactive oxygen species (ROS), acting as essential mediators in biological system, play
important roles in the physiologic and pathologic processes, including cellular signal …

Recent advances of nanotechnology application in autoimmune diseases–A bibliometric analysis

R He, L Li, T Zhang, X Ding, Y Xing, S Zhu, Z Gu, H Hu - Nano Today, 2023 - Elsevier
Autoimmune diseases are a group of serious immune system disorders that are usually
idiopathic and persistent. Currently, autoimmune diseases are often diagnosed after obvious …