Featured Application Radiation therapy treatment planning. Abstract Radiation therapy (RT)
is a constantly evolving therapeutic technique; improvements are continuously being …

Mathematical models of normal tissue complication probability (NTCP) able to robustly
predict radiation-induced morbidities (RIM) play an essential role in the identification of a …

Recently, 2D or 3D methods for dose distribution analysis have been proposed as
evolutions of the Dose Volume Histogram (DVH) approaches. Those methods, collectively …

Purpose To assess hypo-fractionated particle beam therapy (PBT)'s efficacy relative to that
of photon stereotactic body radiotherapy (SBRT) for early stage (ES) non-small cell lung …

Background and purpose To determine whether the impact of heart dose on early overall
survival (OS) reported in RTOG 0617 could be confirmed in an independent cohort …

Cardiac fibrosis is a serious public health problem worldwide that is closely linked to
progression of many cardiovascular diseases (CVDs) and adversely affects both the disease …

Background Radiation therapy plays a major role in the management of adjuvant breast
cancer with nodal involvement, with an iatrogenic increase of cardio-vascular risk. Photon …

Aims Proton therapy is a radiation technique that yields less dose in normal tissues than
photon therapy. In the Netherlands, proton therapy is reimbursed if the reduced dose to …

The improvement of anticancer-therapies results in a greater amount of long-term survivors
after radiotherapy. Therefore, the understanding of cardiotoxicity after irradiation is of …

Purpose Radiation pneumonitis (RP) is commonly associated with thoracic radiation
therapy, and its incidence is related to dose and volume of the normal lung in the path of …