Analytical methods used for the detection and quantification of benzodiazepines

Z Qriouet, Z Qmichou, N Bouchoutrouch… - Journal of analytical …, 2019 - Wiley Online Library
The prescription of psychotropic drugs, especially benzodiazepines (BZDs), occupies a
preponderant place in the management of mental illnesses. Indeed, the BZDs have been …

[HTML][HTML] Benzodiazepines in complex biological matrices: Recent updates on pretreatment and detection methods

YX Zhang, Y Zhang, Y Bian, YJ Liu, A Ren… - Journal of …, 2023 - Elsevier
Benzodiazepines (BDZs) are used in clinics for anxiolysis, anticonvulsants, sedative
hypnosis, and muscle relaxation. They have high consumptions worldwide because of their …

Dispersive micro-solid-phase extraction of benzodiazepines from biological fluids based on polyaniline/magnetic nanoparticles composite

AA Asgharinezhad, H Ebrahimzadeh, F Mirbabaei… - Analytica chimica …, 2014 - Elsevier
In this study, diverse types of Fe 3 O 4 nanocomposites modified by polyaniline, polypyrrole,
and aniline–pyrrole copolymer were synthesized through chemical oxidative polymerization …

Optimization of dispersive liquid–liquid microextraction with central composite design for preconcentration of chlordiazepoxide drug and its determination by HPLC …

S Khodadoust, M Ghaedi - Journal of separation science, 2013 - Wiley Online Library
A simple, rapid, and sensitive method based on dispersive liquid–liquid microextraction
combined with HPLC‐UV detection applied for the quantification of chlordiazepoxide in …

Analytical methodologies for the determination of benzodiazepines in biological samples

K Persona, K Madej, P Knihnicki… - Journal of Pharmaceutical …, 2015 - Elsevier
Benzodiazepine drugs belong to important and most widely used medicaments. They
demonstrate such therapeutic properties as anxiolytic, sedative, somnifacient …

A rapid ultrasound-assisted dispersive liquid–liquid microextraction followed by ultra-performance liquid chromatography for the simultaneous determination of seven …

P Fernández, C González, MT Pena, AM Carro… - Analytica Chimica …, 2013 - Elsevier
A simple and efficient ultrasound-assisted dispersive liquid–liquid microextraction (UA-
DLLME) method has been developed for the determination of seven benzodiazepines …

Determination of low levels of benzodiazepines and their metabolites in urine by hollow-fiber liquid-phase microextraction (LPME) and gas chromatography–mass …

AV de Bairros, RM de Almeida, L Pantaleão… - … of Chromatography B, 2015 - Elsevier
In this study, it is shown a method for the determination of benzodiazepines and their main
metabolites in urine samples by hollow-fiber liquid-phase microextraction (LPME) in the …

On-site rapid screening of benzodiazepines in dietary supplements using pipette-tip micro-solid phase extraction coupled to ion mobility spectrometry

T Sun, MM Ali, D Wang, Z Du - Journal of Chromatography A, 2020 - Elsevier
In this study, a reliable and novel coupling of pipette-tip micro-solid phase extraction (PT-
µSPE) with corona discharge ionization-ion mobility spectrometry (CD-IMS) was developed …

An ultra-sensitive UHPLC-QqQ-MS/MS method for determination of 54 benzodiazepines (pharmaceutical drugs, NPS and metabolites) and z-drugs in biological …

O Wachełko, P Szpot, K Tusiewicz, K Nowak… - Talanta, 2023 - Elsevier
Benzodiazepines exhibit central nervous system depressive activity as well as sedative,
hypnotic, and anticonvulsant properties, which enable to use them as medical treatment in …

Electrochemical determination of nitrazepam by switchable solvent based liquid-liquid microextraction combined with differential pulse voltammetry

S Shahraki, H Ahmar, M Nejati-Yazdinejad - Microchemical Journal, 2018 - Elsevier
In this article, a simple and efficient kind of homogeneous liquid-liquid microextraction based
on an acid–base reaction using switchable-hydrophilicity solvents was proposed for the …