Neuroendocrine differentiation in prostate cancer: a mechanism of radioresistance and treatment failure

CD Hu, R Choo, J Huang - Frontiers in oncology, 2015 - frontiersin.org
Neuroendocrine differentiation (NED) in prostate cancer is a well-recognized phenotypic
change by which prostate cancer cells transdifferentiate into neuroendocrine-like (NE-like) …

Prostate cancer stem-like cells contribute to the development of castration-resistant prostate cancer

D Ojo, X Lin, N Wong, Y Gu, D Tang - Cancers, 2015 - mdpi.com
Androgen deprivation therapy (ADT) has been the standard care for patients with advanced
prostate cancer (PC) since the 1940s. Although ADT shows clear benefits for many patients …

Comprehensive analysis of serum chromogranin A and neuron‐specific enolase levels in localized and castration‐resistant prostate cancer

T Szarvas, A Csizmarik, T Fazekas, A Hüttl… - BJU …, 2021 - Wiley Online Library
Objectives To assess chromogranin A (CGA) and neuron‐specific enolase (NSE) levels and
changes in these at different stages of prostatic adenocarcinoma (PCA). Methods Overall …

Chromogranin A: a useful biomarker in castration-resistant prostate cancer

G Ploussard, F Rozet, G Roubaud, T Stanbury… - World Journal of …, 2023 - Springer
Purpose The natural history of prostate cancer (PC) almost always evolves to castration-
resistant prostate cancer (CRPC) status, sometimes comprising pure or mixed …

[HTML][HTML] Establishment and characterization of two cabazitaxel-resistant prostate cancer cell lines

K Machioka, K Izumi, Y Kadono, H Iwamoto, R Naito… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Once castration-resistant prostate cancer (CRPC) become resistant for cabazitaxel
treatment, the patients are obliged to best supportive care. Therefore, the elucidation of the …

A phase I/II study of the investigational drug alisertib in combination with abiraterone and prednisone for patients with metastatic castration-resistant prostate cancer …

J Lin, SA Patel, AR Sama, JH Hoffman-Censits… - The …, 2016 - academic.oup.com
Abstract Lessons Learned Patients with metastatic castration-resistant prostate cancer did
not tolerate the combination of alisertib with abiraterone and prednisone. There was no clear …

Serum neuroendocrine markers predict therapy outcome of patients with metastatic castration-resistant prostate cancer: a meta-analysis

Y Liu, S Zhao, J Wang, Z Zhu, L Luo, E Li… - Urologia …, 2019 - karger.com
Purpose: To evaluate whether serum neuroendocrine markers could effectively predict
treatment outcomes in patients with metastatic castration-resistant prostate cancer …

Serum levels of chromogranin A are not predictive of high-grade, poorly differentiated prostate cancer: results from an Italian biopsy cohort

C De Nunzio, S Albisinni, F Presicce… - … Oncology: Seminars and …, 2014 - Elsevier
Objectives To explore the association of chromogranin A (CgA) levels and the risk of poorly
differentiated prostate cancer (CaP) in men undergoing prostate biopsy. Materials and …

Predictors for progression of metastatic prostate cancer to castration-resistant prostate cancer in Indians

SK Sureka, R Maheshwari, S Agnihotri… - Indian Journal of …, 2016 - journals.lww.com
Methods: Complete records of 223 of the 489 patients with metastatic PC were obtained
from computerized data based system in a tertiary care hospital in north India between …

ACTH-secreting metastatic prostate cancer with neuroendocrine differentiation

B Hassan, Y Yazbeck, V Akiki, I Salti… - BMJ Case Reports …, 2022 - casereports.bmj.com
Cushing's syndrome (CS) due to ectopic adrenocorticotropic hormone (ACTH) secretion
(EAS) can result from a variety of tumours and rarely from those of prostatic origin. We …