Focal adhesion kinase (FAK, also known as PTK2) is a tyrosine kinase that regulates
integrin and growth factor signaling pathways and is involved in the migration, proliferation …

Key points This study demonstrates and evaluates the changes in rat vascular smooth
muscle cell biomechanics following statin‐mediated cholesterol depletion. Evidence is …

GI mucosal healing requires epithelial sheet migration. The non-receptor tyrosine kinase
focal adhesion kinase (FAK) stimulates epithelial motility. A virtual screen identified the small …

Prior studies suggest that urothelium-released adenosine 5′-triphosphate (ATP) has a
prominent role in bladder mechanotransduction. Urothelial ATP regulates the micturition …

In gastrointestinal smooth muscle, acetylcholine induced muscle contraction is biphasic,
initial peak followed by sustained contraction. Contraction is regulated by phosphorylation of …

Adenosine 5′-triphosphate (ATP) is released in the bladder lumen during filling. Urothelial
ATP is presumed to regulate bladder excitability. Urinary ATP is suggested as a urinary …

Non-steroidal anti-inflammatory drugs (NSAIDs) injure the proximal and distal gut by
different mechanisms. While many drugs reduce gastrointestinal injury, no drug directly …

Antibody-based in situ proximity ligation assays (isPLA) have the potential to study protein
phosphorylation and protein interactions with spatial resolution in intact tissues. However …

Recent studies suggested smooth muscle contraction may involve mechanisms besides the
myosin regulatory light chain (MLC) phosphorylation-induced actomyosin crossbridge …

Objective: This study aimed to conduct proteomic analysis of the sphincter in a neurogenic
bladder caused by T10 spinal cord injury. The differentially expressed proteins (DEPs) of the …