Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure

W Wang, J Yao, W Li, Y Wu, H Duan, C Xu, X Tian… - Clinical …, 2023 - Springer
Background Hypertension is a crucial risk factor for developing cardiovascular disease and
reducing life expectancy. We aimed to detect DNA methylation (DNAm) variants potentially …

[HTML][HTML] Methods in DNA methylation array dataset analysis: A review

K Sahoo, V Sundararajan - Computational and Structural Biotechnology …, 2024 - Elsevier
Understanding the intricate relationships between gene expression levels and epigenetic
modifications in a genome is crucial to comprehending the pathogenic mechanisms of many …

Co-methylation analyses identify CpGs associated with lipid traits in Chinese discordant monozygotic twins

Z Li, W Wang, W Li, H Duan, C Xu, X Tian… - Human Molecular …, 2024 - academic.oup.com
To control genetic background and early life milieu in genome-wide DNA methylation
analysis for blood lipids, we recruited Chinese discordant monozygotic twins to explore the …

Global gene expression profiling and transcription factor network analysis of cognitive aging in monozygotic twins

A Mohammadnejad, W Li, JB Lund, S Li… - Frontiers in …, 2021 - frontiersin.org
Cognitive aging is one of the major problems worldwide, especially as people get older. This
study aimed to perform global gene expression profiling of cognitive function to identify …

Differential methylation patterns from clusters associated with glucose metabolism: evidence from a Shanghai twin study

J Feng, Z Zhu, R Zhou, H Liu, Z Hu, F Wu, H Wang… - …, 2024 - Taylor & Francis
Aim: To assess the associations between genome-wide DNA methylation (DNAm) and
glucose metabolism among a Chinese population, in particular the multisite correlation …

DNA Methylation Mediated the Association of Body Mass Index With Blood Pressure in Chinese Monozygotic Twins

J Yao, F Ning, W Wang, D Zhang - Twin Research and Human …, 2024 - cambridge.org
Obesity is an established risk factor for hypertension, but the mechanisms are only partially
understood. We examined whether body mass index (BMI)-related DNA methylation …

Differential lncRNA expression profiling of cognitive function in middle and old aged monozygotic twins using generalized association analysis

A Mohammadnejad, J Baumbach, W Li, J Lund… - Journal of Psychiatric …, 2021 - Elsevier
Cognitive impairment is the most prominent symptom in neurodegenerative disorders
affecting quality of life and mortality. However, despite years of research, the molecular …

[HTML][HTML] Identifying genetic variants regulating MGMT gene expression-A study in monozygotic Danish twins

A Mohammadnejad, M Soerensen, J Mengel-From… - Genomics, 2023 - Elsevier
Identifying genetic factors affecting the regulation of the O-6-Methylguanine-DNA
Methyltransferase (MGMT) gene and estimating the genetic contribution of the MGMT gene …