On Chip Sorting of Stem Cell-Derived β Cell Clusters Using Traveling Surface Acoustic Waves

N Sethia, JS Rao, Z Khashim, AMR Schornack… - Langmuir, 2024 - ACS Publications
There is a critical need for sorting complex materials, such as pancreatic islets of
Langerhans, exocrine acinar tissues, and embryoid bodies. These materials are cell …

A simple high efficiency protocol for pancreatic islet isolation from mice

D Villarreal, G Pradhan, CS Wu… - Journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Pancreatic islets, also called the Islets of Langerhans, are a cluster of endocrine cells which
produces hormones for glucose regulation and other important biological functions. The …

Blocking TLR4-NF-κB pathway protects mouse islets from the combinatorial impact of high fat and fetuin-A mediated dysfunction and restores ability for insulin …

A Mukhuty, C Fouzder, R Kundu - Molecular and Cellular Endocrinology, 2021 - Elsevier
Lipid mediated pancreatic β-cell dysfunction during Type 2 diabetes is known to be
regulated by activation of TLR4 (Toll Like Receptor 4) and NF-κB (Nuclear factor kappa B) …

[HTML][HTML] A Fresh Look at Islet Isolation from Rabbit Pancreases

E Vasilchikova, P Ermakova, A Bogomolova… - International Journal of …, 2024 - mdpi.com
Islet transplantation represents a promising therapeutic approach for diabetes management,
yet the isolation and evaluation of pancreatic islets remain challenging. This study focuses …

TRPC3 Regulates Islet Beta‐Cell Insulin Secretion

G Rached, Y Saliba, D Maddah, J Hajal… - Advanced …, 2023 - Wiley Online Library
Insulin release is tightly controlled by glucose‐stimulated calcium (GSCa) through hitherto
equivocal pathways. This study investigates TRPC3, a non‐selective cation channel, as a …

[HTML][HTML] Comparative study of the effects of confounding factors on improving rat pancreatic islet isolation yield and quality

M Moazenchi, ASH Nejad, M Izadi, M Khalaj… - Cell Journal …, 2022 - ncbi.nlm.nih.gov
Objective Isolated pancreatic islets are valuable resources for a wide range of research,
including cell replacement studies and cell-based platforms for diabetes drug discovery and …

Revisiting pancreatic islet isolation in murine models: A practical and effective technical protocol

A Fernandes‐da‐Silva, RA Miranda… - Physiological …, 2024 - Wiley Online Library
The endocrine pancreas is composed of clusters of cell groups called pancreatic islets.
These cells are responsible for the synthesis and secretion of hormones crucial for glycemic …

Human pluripotent stem cells: a unique tool for toxicity testing in pancreatic progenitor and endocrine cells

EM MacFarlane, JE Bruin - Frontiers in Endocrinology, 2021 - frontiersin.org
Diabetes prevalence is increasing worldwide, and epidemiological studies report an
association between diabetes incidence and environmental pollutant exposure. There are> …

Stimulation of Insulin Secretion and Inhibition of KATP Channels by Afzelechin and Coniferaldehyde from Ensete glaucum Seeds

LH Trieu, LB Thao, NM Khoi, NTT Huong - Biomedical Research and …, 2024 - bmrat.com
Introduction: Ensete glaucum seeds have been shown to possess antidiabetic properties.
However, the specific hypoglycemic activities of the compounds they contain remain poorly …

小鼠胰岛提取方法改良的实验研究.

曾文, 刘坤莹, 林楚文, 林硕, 彭航娅… - … /Qi Guan Yi Zhi, 2020 - search.ebscohost.com
目的探讨小鼠胰岛提取方法的改良及效果. 方法根据胰岛提取方法不同, 将小鼠随机分为胆总管
穿刺组和胆总管穿刺联合胰腺原位注射组(联合注射组), 每组各100 只. 胰岛提取的改良方法采用 …