Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study
BD Nicholson, J Oke, PS Virdee, DA Harris… - The Lancet …, 2023 - thelancet.com
Background Analysis of circulating tumour DNA could stratify cancer risk in symptomatic
patients. We aimed to evaluate the performance of a methylation-based multicancer early …
patients. We aimed to evaluate the performance of a methylation-based multicancer early …
Primary care patient interest in multi-cancer early detection for cancer screening
RE Myers, MH Hallman, A Shimada, M DiCarlo… - Journal of Personalized …, 2023 - mdpi.com
Multi-cancer early detection (MCED) tests are being developed, but little is known about
patient receptivity to their use for cancer screening. The current study assessed patient …
patient receptivity to their use for cancer screening. The current study assessed patient …
Initially unresectable colorectal liver metastases: the best therapeutic regimens
K Imai, H Baba - The Lancet Oncology, 2023 - thelancet.com
Despite the advances in systemic chemotherapy and molecular targeted therapy, local
treatment, including resection and local ablative treatment, is the only treatment of choice …
treatment, including resection and local ablative treatment, is the only treatment of choice …
Triaging suspected cancer with a multi-Cancer early detection blood test
J Tie - The Lancet Oncology, 2023 - thelancet.com
Notable progress has been made in the field of circulating tumour DNA (ctDNA) analysis
over the past decade. Along the spectrum of promising clinical applications of ctDNA across …
over the past decade. Along the spectrum of promising clinical applications of ctDNA across …
How to Upend Cancer Screening
E Topol - AI in Precision Oncology, 2024 - liebertpub.com
Despite impressive progress in understanding the pathogenesis of cancer over the past
decade, in the United States,> 600,000 people die of cancer annually and∼ 2 million will …
decade, in the United States,> 600,000 people die of cancer annually and∼ 2 million will …