In the present article, a fully three-dimensional human annulus fibrosus model is developed
by considering the regional variation of the complex structural organization of collagen …

Within the consistent daily rhythm of human life, intervertebral discs endure a variety of
complex loads beyond the influences of gravity and muscle forces, leading to significant …

The determinant role of the annulus fibrosus interlamellar zones in the intervertebral disc
transversal and volumetric responses and hence on their corresponding three-dimensional …

In this work, a fully three-dimensional model of the human intervertebral disc is proposed
within a purely analytical framework in the final goal to create time and cost-efficient patient …

Finite element models are useful for investigating internal intervertebral disc (IVD)
behaviours without using disruptive experimental techniques. Simplified geometries are …

Intervertebral disc hernia and dysfunctions are the most common health problems that affect
humans. For this reason, the need of disc prosthetics, and especially annulus fibrosus …

This article presents a multiscale model to predict deformation-induced damage and failure
of human annulus fibrosus under multiaxial loading. In the modeling approach, formulated …

There is an increasing demand to develop predictive medicine through the creation of
predictive models and digital twins of the different body organs. To obtain accurate …

The angle‐ply multilaminate structure of the annulus fibrosus is not reestablished following
discectomy which leads to reherniation of the intervertebral disc (IVD). Biomimetic scaffolds …

The degeneration of the intervertebral disc annulus fibrosus poses significant challenges in
understanding and predicting its mechanical behavior. In this article, we present a novel …