Molecular sensors for NMR-based detection

Z Xu, C Liu, S Zhao, S Chen, Y Zhao - Chemical reviews, 2018 - ACS Publications
Reliable and precise methods capable of unambiguously identifying target analytes in real-
world samples are indispensable in various fields, ranging from biological studies and …

Chemical Sensors Based on Cucurbit[n]uril Macrocycles

S Sinn, F Biedermann - Israel Journal of Chemistry, 2018 - Wiley Online Library
Abstract Cucurbit [n] urils (CBn) are glycoluril‐based macrocyclic hosts that bind many
biologically, medicinally and environmentally relevant analytes with record high affinities in …

Proline editing: A general and practical approach to the synthesis of functionally and structurally diverse peptides. Analysis of steric versus stereoelectronic effects of 4 …

AK Pandey, D Naduthambi, KM Thomas… - Journal of the …, 2013 - ACS Publications
Functionalized proline residues have diverse applications. Herein we describe a practical
approach, proline editing, for the synthesis of peptides with stereospecifically modified …

Oriented circular dichroism: a method to characterize membrane-active peptides in oriented lipid bilayers

J Bürck, P Wadhwani, S Fanghänel… - Accounts of chemical …, 2016 - ACS Publications
Conspectus The structures of membrane-bound polypeptides are intimately related to their
functions and may change dramatically with the lipid environment. Circular dichroism (CD) is …

Membrane-active peptides and the clustering of anionic lipids

P Wadhwani, RF Epand, N Heidenreich, J Bürck… - Biophysical journal, 2012 - cell.com
There is some overlap in the biological activities of cell-penetrating peptides (CPPs) and
antimicrobial peptides (AMPs). We compared nine AMPs, seven CPPs, and a fusion peptide …

[HTML][HTML] Lipid shape is a key factor for membrane interactions of amphipathic helical peptides

E Strandberg, D Tiltak, S Ehni, P Wadhwani… - … et Biophysica Acta (BBA …, 2012 - Elsevier
The membrane alignment of the amphiphilic α-helical model peptide MSI-103 (sequence
[KIAGKIA] 3-NH2) was examined by solid state 2H-NMR in different lipid systems by …

3D hydrophobic moment vectors as a tool to characterize the surface polarity of amphiphilic peptides

S Reißer, E Strandberg, T Steinbrecher, AS Ulrich - Biophysical journal, 2014 - cell.com
The interaction of membranes with peptides and proteins is largely determined by their
amphiphilic character. Hydrophobic moments of helical segments are commonly derived …

Antibiotic gold: tethering of antimicrobial peptides to gold nanoparticles maintains conformational flexibility of peptides and improves trypsin susceptibility

P Wadhwani, N Heidenreich, B Podeyn, J Bürck… - Biomaterials …, 2017 - pubs.rsc.org
Peptide-coated nanoparticles are valuable tools for diverse biological applications, such as
drug delivery, molecular recognition, and antimicrobial action. The functionalization of pre …

Orientation and dynamics of peptides in membranes calculated from 2H-NMR data

E Strandberg, S Esteban-Martín, J Salgado, AS Ulrich - Biophysical Journal, 2009 - cell.com
Solid-state 2 H-NMR is routinely used to determine the alignment of membrane-bound
peptides. Here we demonstrate that it can also provide a quantitative measure of the …

Fluorinated amino acids in amyloid formation: a symphony of size, hydrophobicity and α-helix propensity

UIM Gerling, M Salwiczek, CD Cadicamo… - Chemical …, 2014 - pubs.rsc.org
Fluorinated amino acids can have dramatic effects on protein stability and protein–protein
interactions due to the unique stereoelectronic properties of fluorine. Previous approaches …