Risk factors for childhood and adult primary brain tumors

QT Ostrom, M Adel Fahmideh, DJ Cote… - Neuro …, 2019 - academic.oup.com
Primary brain tumors account for~ 1% of new cancer cases and~ 2% of cancer deaths in the
United States; however, they are the most commonly occurring solid tumors in children …

Systematic review of Mendelian randomization studies on risk of cancer

G Markozannes, A Kanellopoulou, O Dimopoulou… - BMC medicine, 2022 - Springer
Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

Sleep duration, genetic susceptibility, and Alzheimer's disease: a longitudinal UK Biobank-based study

S Yuan, W Ma, R Yang, F Xu, D Han, T Huang, MI Peng… - BMC geriatrics, 2022 - Springer
Background Alzheimer's disease (AD) is the most frequently occurring type of dementia.
Concurrently, inadequate sleep has been recognized as a public health epidemic. Notably …

Epidemiology, risk factors, and prognostic factors of gliomas

A Pellerino, M Caccese, M Padovan, G Cerretti… - Clinical and …, 2022 - Springer
Purpose Diffuse gliomas are the most common primary malignant brain tumors in adults.
Many studies analyzed their epidemiology, such as the incidence and mortality. Moreover …

Severe mental illness and the risk of breast cancer: A two-sample, two-step multivariable Mendelian randomization study

Y Cui, W Lu, T Shao, Z Zhuo, Y Wang, W Zhang - Plos one, 2023 - journals.plos.org
Background Based on epidemiological reports, severe mental illness (SMI) and breast
cancer (BC) risk are linked positively. However, it is susceptible to clinical confounding …

Pre-diagnostic blood biomarkers for adult glioma

LJ Andrews, P Davies, C Herbert, KM Kurian - Frontiers in Oncology, 2023 - frontiersin.org
Glioma is one of the most common malignant primary brain tumours in adults, of which,
glioblastoma is the most prevalent and malignant entity. Glioma is often diagnosed at a later …

Epidemiology, genetic epidemiology and Mendelian randomisation: more need than ever to attend to detail

NA Sheehan, V Didelez - Human genetics, 2020 - Springer
In the current era, with increasing availability of results from genetic association studies,
finding genetic instruments for inferring causality in observational epidemiology has become …

Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study

AE Howell, JW Robinson, RE Wootton, A McAleenan… - Bmc Cancer, 2020 - Springer
Background Whilst epidemiological studies have provided evidence of associations
between certain risk factors and glioma onset, inferring causality has proven challenging …

Hill's Temporality criterion: reverse causation and its radiation aspect

AN Koterov, LN Ushenkova, AP Biryukov - Biology Bulletin, 2020 - Springer
This review considers various aspects of the temporality causation criterion and the
corresponding confounders within the framework of temporal bias, including facts for …

[HTML][HTML] Causal Inference and Annotation of Phosphoproteomics Data in Multi-omics Cancer Studies

Q Dong, M Tan, Y Zhou, Y Zhang, J Li - Molecular & Cellular Proteomics, 2025 - Elsevier
Protein phosphorylation plays a crucial role in regulating diverse biological processes.
Perturbations in protein phosphorylation are closely associated with downstream pathway …