Obesity is a chronic illness associated with several metabolic derangements and
comorbidities (ie, insulin resistance, leptin resistance, diabetes, etc.) and often leads to …

Abstract Background This Obesity Medicine Association (OMA) Clinical Practice Statement
(CPS) is intended to provide clinicians an overview of type 2 diabetes mellitus (T2DM), an …

In clinical practice, we often deal with patients who suffer from non-alcoholic fatty liver
disease (NAFLD) concurrent with type 2 diabetes mellitus (T2DM). The etiopathogenesis of …

Type 2 diabetes (T2D) and Alzheimer's diseases (AD) represent major health issues that
have reached alarming levels in the last decades. Although growing evidence demonstrates …

Aim To assess the relationship between HbA1c and body weight reductions with tirzepatide
treatment (5, 10 or 15 mg). Materials and Methods HbA1c and body weight data at 40 weeks …

Functional hypogonadotropic hypogonadism (FHH) is an increasingly frequent condition,
whose pathological mechanisms are not yet fully clarified. The concept of FHH has now …

Excessive insulin secretion independent of insulin resistance, defined as primary
hypersecretion, is associated with obesity and an unfavorable metabolic phenotype. We …

Introduction CCN5/WISP2 is prominently manifest in adipose tissue and has been linked to
the pathogenesis of obesity, diabetes, and insulin resistance. However, discrepancies exist …

Background Over the last decades, various approaches have been explored to restore
sufficient β-cell mass in diabetic patients. Stem cells are certainly an attractive source of new …

Background Adaptive thermogenesis represents the main mechanism through which the
body generates heat in response to external stimuli, a phenomenon that includes shivering …