RNA-Seq technology and its application in fish transcriptomics

X Qian, Y Ba, Q Zhuang, G Zhong - Omics: a journal of integrative …, 2014 - liebertpub.com
High-throughput sequencing technologies, also known as next-generation sequencing
(NGS) technologies, have revolutionized the way that genomic research is advancing. In …

Transcriptome analysis based on RNA-Seq in understanding pathogenic mechanisms of diseases and the immune system of fish: a comprehensive review

A Sudhagar, G Kumar, M El-Matbouli - International journal of molecular …, 2018 - mdpi.com
In recent years, with the advent of next-generation sequencing along with the development
of various bioinformatics tools, RNA sequencing (RNA-Seq)-based transcriptome analysis …

Transcriptome analysis revealed changes of multiple genes involved in immunity in Cynoglossus semilaevis during Vibrio anguillarum infection

X Zhang, S Wang, S Chen, Y Chen, Y Liu… - Fish & shellfish …, 2015 - Elsevier
Half-smooth tongue sole (Cynoglossus semilaevis) is one of the most valuable marine
aquatic species in Northern China. Given to the rapid development of aquaculture industry …

Characterization of the Japanese flounder NLRP3 inflammasome in restricting Edwardsiella piscicida colonization in vivo

H Chen, S Ding, J Tan, D Yang, Y Zhang… - Fish & shellfish …, 2020 - Elsevier
NLRP3 inflammasome is one of the most well-known inflammasomes in mammals, which
plays critical roles in innate immunity. However, knowledge about this inflammasome in non …

[HTML][HTML] The dynamic chromatin architecture of the regenerating liver

AW Wang, YJ Wang, AM Zahm, AR Morgan… - Cellular and molecular …, 2020 - Elsevier
Background & Aims The adult liver is the main detoxification organ and routinely is exposed
to environmental insults but retains the ability to restore its mass and function upon tissue …

Antigen presentation and autophagy in teleost adaptive immunity

C Johnstone, E Chaves-Pozo - International Journal of Molecular …, 2022 - mdpi.com
Infectious diseases are a burden for aquaculture. Antigen processing and presentation
(APP) to the immune effector cells that fight pathogens is key in the adaptive immune …

Gene expression profiling in live attenuated Edwardsiella tarda vaccine immunized and challenged zebrafish: insights into the basic mechanisms of protection seen in …

D Yang, Q Liu, C Ni, S Li, H Wu, Q Wang, J Xiao… - Developmental & …, 2013 - Elsevier
Despite the importance and success of vaccine immunization against bacterial diseases in
fish, little is known about the molecular mechanisms of vaccine-induced immune protection …

Transcriptome profiling based on protein–protein interaction networks provides a core set of genes for understanding blood immune response mechanisms against …

Z Li, X Liu, J Liu, K Zhang, H Yu, Y He, X Wang… - Developmental & …, 2018 - Elsevier
Marine organisms are commonly under threat from various pathogens. Edwardsiella tarda is
one of the fish pathogens that can infect both cultured and wild fish species. E. tarda can …

Comparative study of immune reaction against bacterial infection from transcriptome analysis

S Maekawa, PC Wang, SC Chen - Frontiers in Immunology, 2019 - frontiersin.org
Transcriptome analysis is a powerful tool that enables a deep understanding of complicated
physiological pathways, including immune responses. RNA sequencing (RNA-Seq)-based …

Intracellular bacterial infections: a challenge for developing cellular mediated immunity vaccines for farmed fish

HM Munang'andu - Microorganisms, 2018 - mdpi.com
Aquaculture is one of the most rapidly expanding farming systems in the world. Its rapid
expansion has brought with it several pathogens infecting different fish species. As a result …