Infectious agents and neurodegeneration
G De Chiara, ME Marcocci, R Sgarbanti, L Civitelli… - Molecular …, 2012 - Springer
A growing body of epidemiologic and experimental data point to chronic bacterial and viral
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …
[HTML][HTML] Drosophila as a genetic model for studying pathogenic human viruses
TT Hughes, AL Allen, JE Bardin, MN Christian… - Virology, 2012 - Elsevier
Viruses are infectious particles whose viability is dependent on the cells of living organisms,
such as bacteria, plants, and animals. It is of great interest to discover how viruses function …
such as bacteria, plants, and animals. It is of great interest to discover how viruses function …
Clathrin-nanoparticles deliver BDNF to hippocampus and enhance neurogenesis, synaptogenesis and cognition in HIV/neuroAIDS mouse model
Brain derived neurotrophic factor (BDNF) promotes the growth, differentiation, maintenance
and survival of neurons. These attributes make BDNF a potentially powerful therapeutic …
and survival of neurons. These attributes make BDNF a potentially powerful therapeutic …
Human immunodeficiency virus promotes mitochondrial toxicity
Combined antiretroviral therapies (cART) have had remarkable success in reducing
morbidity and mortality among patients infected with human immunodeficiency virus (HIV) …
morbidity and mortality among patients infected with human immunodeficiency virus (HIV) …
[HTML][HTML] Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS
DJ Hermes, C Xu, JL Poklis, MJ Niphakis, BF Cravatt… - …, 2018 - Elsevier
The HIV-1 transactivator of transcription (Tat) is a neurotoxin involved in the pathogenesis of
HIV-1 associated neurocognitive disorders (HAND). The neurotoxic effects of Tat are …
HIV-1 associated neurocognitive disorders (HAND). The neurotoxic effects of Tat are …
Role of oxidative stress in HIV-1-associated neurocognitive disorder and protection by gene delivery of antioxidant enzymes
JP Louboutin, D Strayer - Antioxidants, 2014 - mdpi.com
HIV encephalopathy covers a range of HIV-1-related brain dysfunction. In the Central
Nervous System (CNS), it is largely impervious to Highly Active AntiRetroviral Therapy …
Nervous System (CNS), it is largely impervious to Highly Active AntiRetroviral Therapy …
Hippocampal up-regulation of apolipoprotein D in a rat model of maternal hypo-and hyperthyroidism: implication of oxidative stress
M Salami, AR Bandegi, HR Sameni, AA Vafaei… - Neurochemical …, 2019 - Springer
Thyroid disorders impair various functions of the hippocampus where thyroid hormone
receptors are localized in the brain. Hyper and hypothyroidism are associated with large …
receptors are localized in the brain. Hyper and hypothyroidism are associated with large …
HIV-associated neurodegeneration: exploitation of the neuronal cytoskeleton
ED Wenzel, V Avdoshina, I Mocchetti - Journal of neurovirology, 2019 - Springer
Abstract Human immunodeficiency virus-1 (HIV) infection of the central nervous system
damages synapses and promotes axonal injury, ultimately resulting in HIV-associated …
damages synapses and promotes axonal injury, ultimately resulting in HIV-associated …
Pathogenesis and treatment of HIV infection: the cellular, the immune system and the neuroendocrine systems perspective
VA Chereshnev, G Bocharov, S Bazhan… - International reviews …, 2013 - Taylor & Francis
Infections with HIV represent a great challenge for the development of strategies for an
effective cure. The spectrum of diseases associated with HIV ranges from opportunistic …
effective cure. The spectrum of diseases associated with HIV ranges from opportunistic …
Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev
E Eren, NR Watts, D Randazzo, I Palmer, DL Sackett… - Structure, 2023 - cell.com
HIV-1 Rev is an essential regulatory protein that transports unspliced and partially spliced
viral mRNAs from the nucleus to the cytoplasm for the expression of viral structural proteins …
viral mRNAs from the nucleus to the cytoplasm for the expression of viral structural proteins …