Paracrine mechanisms of mesenchymal stromal cells in angiogenesis

S Maacha, H Sidahmed, S Jacob… - Stem cells …, 2020 - Wiley Online Library
The role of the mesenchymal stromal cell‐(MSC‐) derived secretome is becoming
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …

[HTML][HTML] Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design

SAA Kooijmans, OG de Jong, RM Schiffelers - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are submicron cell-secreted structures containing proteins,
nucleic acids and lipids. EVs can functionally transfer these cargoes from one cell to another …

Extracellular Vesicle-derived circular RNAs confers chemoresistance in Colorectal cancer

KW Hon, NS Ab-Mutalib, NMA Abdullah, R Jamal… - Scientific reports, 2019 - nature.com
Chemo-resistance is associated with poor prognosis in colorectal cancer (CRC), with the
absence of early biomarker. Exosomes are microvesicles released by body cells for …

Electrokinetically driven exosome separation and concentration using dielectrophoretic-enhanced PDMS-based microfluidics

S Ayala-Mar, VH Perez-Gonzalez… - Analytical …, 2019 - ACS Publications
Exosomes are a specific subpopulation of extracellular vesicles that have gained interest
because of their many potential biomedical applications. However, exosome isolation and …

Microfluidic tools for enhanced characterization of therapeutic stem cells and prediction of their potential antimicrobial secretome

P Marrazzo, V Pizzuti, S Zia, A Sargenti, D Gazzola… - Antibiotics, 2021 - mdpi.com
Antibiotic resistance is creating enormous attention on the development of new antibiotic-
free therapy strategies for bacterial diseases. Mesenchymal stromal stem cells (MSCs) are …

miR‐543 in human mesenchymal stem cell–derived exosomes promotes cardiac microvascular endothelial cell angiogenesis after myocardial infarction through …

M Yang, X Liu, M Jiang, J Li, Y Tang, L Zhou - IUBMB life, 2021 - Wiley Online Library
To explore the impact and mechanism of human mesenchymal stem cells (hMSCs) on the
angiogenesis of cardiac microvascular endothelial cells (CMECs) after ischemia insult …

[HTML][HTML] Next generation of neurological therapeutics: Native and bioengineered extracellular vesicles derived from stem cells

S Jin, Z Lv, L Kang, J Wang, C Tan, L Shen… - Asian Journal of …, 2022 - Elsevier
Extracellular vesicles (EVs)-based cell-free therapy, particularly stem cell-derived
extracellular vesicles (SC-EVs), offers new insights into treating a series of neurological …

A comorbidity model of myocardial ischemia/reperfusion injury and hypercholesterolemia in rat cardiac myocyte cultures

A Makkos, Á Szántai, J Pálóczi, J Pipis, B Kiss… - Frontiers in …, 2020 - frontiersin.org
Introduction The use of comorbidity models is crucial in cardioprotective drug development.
Hypercholesterolemia causes endothelial and myocardial dysfunction, as well as …

A tailored lipid supplement restored membrane fatty acid composition and ameliorates in vitro biological features of human amniotic epithelial cells

V Pizzuti, PM Abruzzo, A Chatgilialoglu, S Zia… - Journal of Clinical …, 2022 - mdpi.com
Cell culture conditions influence several biological and biochemical features of stem cells
(SCs), including the membrane lipid profile, thus limiting the use of SCs for cell therapy …

Possible mechanism of placental mesenchymal stem cell-derived neural cell transplantation on the recovery of neurogenic bladder function after spinal cord injury

M Yao, G Liu, Y Li, H Song - Cellular and Molecular Biology, 2021 - mail.cellmolbiol.org
After spinal cord injury, more neurogenic bladder function is caused. The purpose of this
article is to investigate the possible mechanism of placental mesenchymal stem cell-derived …