Although much is known about the regenerative capacity of retinal ganglion cells, very
significant barriers remain in our ability to restore visual function following traumatic injury or …

Damage to the central nervous system (CNS) of fish can often be repaired to restore
function, but in mammals recovery from CNS injuries usually fails due to a lack of axon …

Triphenyl phosphate (TPhP), a typical organophosphate ester, is frequently detected in the
environment and biota samples. It has been implicated as a neurotoxin as its structure is …

Peripheral nerve injuries represent one of the most common causes of permanent
disabilities. Therapeutic electrical stimulation has been widely used in neural regeneration …

Peripheral nerve injury can cause various degrees of damage to the morphological structure
and physiological function of the peripheral nerve. At present, compared with “gold …

The flame retardants hexabromobenzene (HBB) and pentabromobenzene (PBB) have been
extensively used and become ubiquitous pollutants in the aquatic environment and biota …

Microcystin-LR (MCLR) is a commonly acting potent hepatotoxin and has been pointed out
of potentially causing developmental neurotoxicity, but the exact mechanism is little known …

Decabromodiphenyl ethane (DBDPE), a widely used novel brominated flame retardant, is
gaining concerns due to rapidly increased contents in various environmental and biota …

Highlights•Zebrafish embryos were exposed to different concentrations of PFHxA for 120
h.•PFHxA have no significant neurodevelopmental effects under acute low-dose …

Facilitating axon regeneration in the injured central nervous system remains a challenging
task. RAF-MAP2K signaling plays a key role in axon elongation during nervous system …