Insights into Hyperparathyroidism–Jaw Tumour Syndrome: From Endocrine Acumen to the Spectrum of CDC73 Gene and Parafibromin-Deficient Tumours

AM Gheorghe, OC Sima, AF Florescu, A Ciuche… - International Journal of …, 2024 - mdpi.com
A total of 1 out of 10 patients with primary hyperparathyroidism (PHP) presents an
underlying genetic form, such as multiple endocrine neoplasia types 1, 2A, etc., as well as …

[HTML][HTML] Neuroendocrine parathyroid tumors: quality of life in patients with primary hyperparathyroidism

M Carsote, C Nistor, M Stanciu, FL Popa, RC Cipaian… - Biomedicines, 2023 - mdpi.com
Tumors of the parathyroid glands, when associated with PTH (parathyroid hormone) excess,
display a large area of complications; in addition to the classical clinical picture of primary …

Genomic profiling reveals the variant landscape of sporadic parathyroid adenomas in Chinese population

X Tao, T Xu, X Lin, S Xu, Y Fan, B Guo… - The Journal of …, 2023 - academic.oup.com
Objective To define somatic variants of parathyroid adenoma (PA) and to provide novel
insights into the underlying molecular mechanism of sporadic PA. Methods Basic clinical …

The clinicopathological features of lung metastases of parathyroid cancinoma

Q Li, Z Shi, X Zhou, M Xu, T Zhao, B Wei… - … -Research and Practice, 2024 - Elsevier
Parathyroid carcinoma (PC) is an extremely rare malignant tumor of the parathyroid glands.
The lung is the most common target organ for PC distant metastases. In this study, twelve …

[HTML][HTML] Primary hyperparathyroidism: predictors of sporadic multi-gland disease

L Yang, X Jing, H Pang, L Guan… - Endocrine Connections, 2024 - ec.bioscientifica.com
In this review, we discuss the definition, prevalence, and etiology of sporadic multiglandular
disease (MGD), with an emphasis on its preoperative and intraoperative predictors. Primary …

Vascular mimicry and mosaic vessels in parathyroid tumours: a new diagnostic approach?

M Falleni, M Dal Lago, D Tosi, G Ghilardi… - Journal of Clinical …, 2024 - jcp.bmj.com
Aims Evaluation of 'alternative'vascularisation in human cancer is considered an important
prognostic parameter; the 2022 WHO classification of parathyroid tumours despite …

[HTML][HTML] Somatostatin Receptor Imaging in the Diagnosis and Management of Parathyroid Neuroendocrine Neoplasia

U Tsoy, K Pogosian, D Ryzhkova, O Yudina… - Diagnostics, 2024 - mdpi.com
Background: Parathyroid tumors are classified as parathyroid neuroendocrine neoplasia
(NEN) by the IARC-WHO classification. These tumors can occur with NENs from other sites …

The pharmacokinetics, pharmacodynamics and tolerability of SHR6508 in chinese healthy subjects: a randomized, placebo-controlled, double-blind, single-dose and …

S Zhang, H Tan, S Yang, X Yang, C Cui… - Naunyn-Schmiedeberg's …, 2024 - Springer
This study aimed to evaluate the pharmacokinetics (PK), pharmacodynamics (PD), safety,
and tolerability of SHR6508 injection, a new calcimimetic agent, in healthy Chinese subjects …

Special Issue on Neuroendocrine Tumors: Updates on Classification Systems, Streamlining Diagnosis, and Emphasis on Molecular Signatures in Neuroendocrine …

MA Gubbiotti, KT Montone, Z Baloch - Advances in anatomic …, 2023 - journals.lww.com
The tremendous expansion of knowledge regarding the intricacies of cell signaling
pathways, including tracing tumor cell lineage and identifying unique molecular signatures …

[HTML][HTML] Large atypical parathyroid tumor-a diagnostic conundrum

S Mitra, S Satpathy, D Banerjee… - Autopsy and Case …, 2024 - SciELO Brasil
Atypical parathyroid tumor (APT) is a rare neoplasm of the parathyroid gland, which shows
atypical cytological or architectural features and lacks definite diagnosis criteria for …