Early life stress (ELS), in the form of childhood maltreatment, abuse, or neglect, increases
the risk for psychiatric sequelae later in life. The neurobiology of response to early stress …

Drug use is a choice with immediate positive outcomes, but long-term negative
consequences. Thus, the repeated use of drugs in the face of negative consequences …

Background Polysubstance use (PSU) is prevalent among individuals with substance use
disorders, but the vast majority of preclinical substance use research has focused on …

Backgrounds More males than females play video games and develop problems with
gaming. However, little is known regarding how males and females who game on the …

Classical psychedelics, primarily psilocybin and lysergic acid diethylamide (LSD), have
been used and extensively studied in Western medicine as part of substance-assisted …

Background Previous voxel-based morphometric (VBM) and functional magnetic resonance
imaging (fMRI) studies have shown changes in brain structure and function in cocaine …

Social rewards are strong drivers of behavior and fundamental to well-being, yet there is a
lack of consensus regarding what actually defines a reward as “social.” Because a …

People often align their behaviors with group opinions, known as social conformity. Many
neuroscience studies have explored the neuropsychological mechanisms underlying social …

Abstract Internet Gaming Disorder (IGD) is a behavioural addiction characterised by
excessive exposure to addictive stimuli, resulting in reduced sensitivity of the brain's reward …

Highlights•Stimulant users display specific impairments in social cognition and
interaction.•Cocaine users show blunted responses of the reward system to social …