Many people simply recognise turmeric; the golden-coloured powder as a spice,
experimental and clinical research, has however, shown that the remedies of various …

Polymorphism occurs widely in pharmaceutical solids, and must be thoroughly studied
during product development. Twenty-four years after ritonavir (RTV) Form II materialized, we …

The fundamental crystal science underpinning the industrial crystallisation of organic
materials is reviewed from molecular, intermolecular (synthonic) and crystallographic …

Direct-acting antiviral regimens have transformed therapeutic management of hepatitis C
across all prevalent genotypes. Most of the chemical matter in these regimens comprises …

Organic compounds can crystallize in different forms known as polymorphs. Discovery and
control of polymorphism is crucial to the pharmaceutical industry since different polymorphs …

The study presents a thorough and detailed analysis of bicalutamide's structural and
conformational properties. Quantum chemical calculations were employed to explore the …

Propose The propose is to investigate the reasons for the insolubility of Form III in water and
to explore the mechanism of the hydration process of Form III. Methods The conformational …

Hot-melt extrusion (HME) is a technology increasingly common for the commercial
production of pharmaceutical amorphous solid dispersions (ASDs), especially for poorly …

The modification of crystal shapes is used intensively in designing particles with desired
properties to ensure the efficiency of the manufacturing processes. In this work, urea crystals …

Molecular-scale modelling for predicting surface energies on a face-specific and whole
particle basis is applied to all the crystallographically-independent surfaces of L-glutamic …