Zn2+ ions are essential in many physiological processes, including enzyme catalysis,
protein structural stabilization, and the regulation of many proteins. The affinities of proteins …

Copper (Cu) is an essential trace element for all living organisms and used as cofactor in
key enzymes of important biological processes, such as aerobic respiration or superoxide …

Transition metals function as structural and catalytic cofactors for a large diversity of proteins
and enzymes that collectively comprise the metalloproteome. Metallostasis considers all …

The cellular prion protein (PrP C) comprises two domains: a globular C-terminal domain and
an unstructured N-terminal domain. Recently, copper has been observed to drive tertiary …

Background Biological denitrification has been commonly adopted for the removal of
nitrogen from sewage effluents. However, due to the low temperature during winter …

The resistance of gram-negative bacteria to silver ions is mediated by a silver efflux pump,
which mainly relies on a tripartite efflux complex SilCBA, a metallochaperone SilF and an …

Copper is essential in cells as a cofactor for key redox enzymes. Bacteria have acquired
molecular components that sense, uptake, distribute, and expel copper ensuring that …

CopG is an uncharacterized protein ubiquitous in Gram-negative bacteria whose gene
frequently occurs in clusters of copper resistance genes and can be recognized by the …

Heme-regulatory motifs (HRMs) are present in many proteins that are involved in diverse
biological functions. The C-terminal tail region of human heme oxygenase-2 (HO2) contains …

An important question is whether consensus mechanisms for copper monooxygenase
enzymes such as peptidylglycine monooxygenase (PHM) and dopamine β-monooxygenase …