Sonic hedgehog (Shh) signaling is an essential central nervous system (CNS) pathway
involved during embryonic development and later life stages. Further, it regulates cell …

Impact to the head or rapid head acceleration–deceleration can cause traumatic brain injury
(TBI) with a characteristic pathology of traumatic axonal injury (TAI) and secondary damage …

White matter tracts are highly vulnerable to damage from impact-acceleration forces of
traumatic brain injury (TBI). Mild TBI is characterized by a low density of traumatic axonal …

Traumatic brain injury (TBI) patients often exhibit slowed information processing speed that
can underlie diverse symptoms. Processing speed depends on neural circuit function at …

Traumatic brain injury (TBI) is a complex condition that can resolve over time but all too often
leads to persistent symptoms, and the risk of poor patient outcomes increases with aging …

Traumatic brain injury (TBI) is common in both civilian and military life, placing a large
burden on survivors and society. However, with the recognition of neural stem cells in adult …

Astrocytes are complex cells that perform a broad array of essential functions in the healthy
and injured nervous system. The recognition that these cells are integral components of …

Noninvasive detection of mild traumatic brain injury (mTBI) is important for evaluating acute
through chronic effects of head injuries, particularly after repetitive impacts. To better detect …

Traumatic brain injury (TBI) is a major contributor to disability and death worldwide, and
manifests in cognitive, behavioral, and motor impairment. Although there have been …

The homeostasis of the neurovascular unit (NVU) is disrupted after traumatic brain injury
(TBI), and therapeutic strategies targeting the NVU would likely improve neurological …