Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Kapil Sahnan specialist registrar in colorectal surgery1, Samuel O Adegbola specialist
registrar in colorectal surgery1, Phillip J Tozer specialist registrar in colorectal surgery1 …

Background & Aims Therapies for perianal fistulas in patients with Crohn's disease are often
ineffective in producing long-term healing. We performed a randomized placebo-controlled …

1.1. Aim The overarching aim of ECCO is to improve the care of patients with IBD through
the development of guidelines, education and research. Current evidence is fundamental in …

AIM To systematically review the literature on epidemiology, disease burden, and treatment
outcomes for Crohn's disease (CD) patients with complex perianal fistulas. METHODS …

Anal fistulas continue to be a problem for patients and surgeons alike despite scientific
advances. While patient and anatomical characteristics are important to surgeons who are …

Since the introduction of the first anti-tumor necrosis factor antibodies in the late 1990s,
biologic therapy has revolutionized the medical treatment of patients with inflammatory …

Background Exosome administration is a novel medical approach that promises excellent
immunomodulatory properties without the conventional side effects of current antitumor …

Background Progression from anorectal abscess to fistula is poorly described and it remains
unclear which patients develop a fistula following an abscess. The aim was to assess the …

Patients with Crohn's disease often develop perianal disease, successfully managed in most
cases. However, its most aggressive form, complex perianal disease, is associated with high …