The extended granin family: structure, function, and biomedical implications

A Bartolomucci, R Possenti, SK Mahata… - Endocrine …, 2011 - academic.oup.com
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

Role of catestatin in the cardiovascular system and metabolic disorders

E Zalewska, P Kmieć, K Sworczak - Frontiers in cardiovascular …, 2022 - frontiersin.org
Catestatin is a multifunctional peptide that is involved in the regulation of the cardiovascular
and immune systems as well as metabolic homeostatis. It mitigates detrimental, excessive …

Chromogranin A and its fragments in cardiovascular, immunometabolic, and cancer regulation

SK Mahata, A Corti - Annals of the New York Academy of …, 2019 - Wiley Online Library
Chromogranin A (CgA)—the index member of the chromogranin/secretogranin secretory
protein family—is ubiquitously distributed in endocrine, neuroendocrine, and immune cells …

The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism

T Angelone, AM Quintieri, BK Brar… - …, 2008 - academic.oup.com
Circulating levels of catestatin (Cts; human chromogranin A352–372) decrease in the
plasma of patients with essential hypertension. Genetic ablation of the chromogranin A …

Reprint of: catestatin: a multifunctional peptide from Chromogranin A

SK Mahata, M Mahata, MM Fung, DT O'Connor - Regulatory peptides, 2010 - Elsevier
In 1997, we identified a novel peptide, catestatin (CST: bovine chromogranin A [CHGA] 344–
364: RSMRLSFRARGYGFRGPGLQL; human CHGA352–372 …

Granin-derived peptides

J Troger, M Theurl, R Kirchmair, T Pasqua, B Tota… - Progress in …, 2017 - Elsevier
The granin family comprises altogether 7 different proteins originating from the diffuse
neuroendocrine system and elements of the central and peripheral nervous systems. The …

Catestatin as a target for treatment of inflammatory diseases

EM Muntjewerff, G Dunkel, MJT Nicolasen… - Frontiers in …, 2018 - frontiersin.org
It is increasingly clear that inflammatory diseases and cancers are influenced by cleavage
products of the pro-hormone chromogranin A (CgA), such as the 21-amino acids long …

Serum markers in small cell lung cancer: opportunities for improvement

M Harmsma, B Schutte, FCS Ramaekers - Biochimica et Biophysica Acta …, 2013 - Elsevier
Lung cancer is one of the leading causes of death from malignancy worldwide. In particular
small cell lung cancers, which comprise about 15–20% of all lung cancers, are extremely …

[HTML][HTML] Catestatin peptide of chromogranin A as a potential new target for several risk factors management in the course of metabolic syndrome

Y Bourebaba, M Mularczyk, K Marycz… - Biomedicine & …, 2021 - Elsevier
Obesity, lipodystrophy, diabetes, and hypertension collectively constitute the main features
of Metabolic Syndrome (MetS), together with insulin resistance (IR), which is considered as …

Monocyte migration: a novel effect and signaling pathways of catestatin

M Egger, AGE Beer, M Theurl, W Schgoer… - European journal of …, 2008 - Elsevier
Several members of the neuropeptide family exert chemotactic actions on blood monocytes
consistent with neurogenic inflammation. Furthermore, chromogranin A (CgA) containing …