Mesenchymal stem cell secretome as an emerging cell-free alternative for improving wound repair

P Ahangar, SJ Mills, AJ Cowin - International journal of molecular …, 2020 - mdpi.com
The use of mesenchymal stem cells (MSC) for the treatment of cutaneous wounds is
currently of enormous interest. However, the broad translation of cell therapies into clinical …

Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts

Y Tan, RC Coyle, RW Barrs, SE Silver, M Li… - Science …, 2023 - science.org
Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …

Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction

SJ Park, RY Kim, BW Park, S Lee, SW Choi… - Nature …, 2019 - nature.com
Since both myocardium and vasculature in the heart are excessively damaged following
myocardial infarction (MI), therapeutic strategies for treating MI hearts should concurrently …

Induced pluripotent stem cells 10 years later: for cardiac applications

Y Yoshida, S Yamanaka - Circulation research, 2017 - Am Heart Assoc
Induced pluripotent stem cells (iPSCs) are reprogrammed cells that have features similar to
embryonic stem cells, such as the capacity of self-renewal and differentiation into many …

Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers

BA Aguado, W Mulyasasmita, J Su… - … Engineering Part A, 2012 - liebertpub.com
Cell transplantation is a promising therapy for a myriad of debilitating diseases; however,
current delivery protocols using direct injection result in poor cell viability. We demonstrate …

Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling

KH Griffin, SW Fok, J Kent Leach - NPJ Regenerative Medicine, 2022 - nature.com
Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to
address defects arising from trauma, inefficient wound repair, or congenital malformation …

Exosomes released from educated mesenchymal stem cells accelerate cutaneous wound healing via promoting angiogenesis

X Qiu, J Liu, C Zheng, Y Su, L Bao, B Zhu… - Cell …, 2020 - Wiley Online Library
Objectives Skin serves as the major interface between the external environment and body
which is liable to many kinds of injuries. Mesenchymal stem cell (MSC) therapy has been …

[HTML][HTML] In situ delivery of apoptotic bodies derived from mesenchymal stem cells via a hyaluronic acid hydrogel: a therapy for intrauterine adhesions

L Xin, C Wei, X Tong, Y Dai, D Huang, J Chen, L Ma… - Bioactive materials, 2022 - Elsevier
Stem cell-based and stem cell-derived exosome-based therapies have shown promising
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …

Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts

MA Laflamme, KY Chen, AV Naumova… - Nature …, 2007 - nature.com
Cardiomyocytes derived from human embryonic stem (hES) cells potentially offer large
numbers of cells to facilitate repair of the infarcted heart. However, this approach has been …