Over the past decade, a number of new 1, 4-naphthoquinones have been isolated from
natural sources and new 1, 4-naphthoquinones with diverse structural features have been …

Atovaquone belongs to a naphthoquinone class of drugs and is used in combination with
proguanil (Malarone) for the treatment of acute, uncomplicated malaria caused by …

The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …

Background: Naphthoquinones are natural pigments that are widely distributed in nature
and have important biological activities. Lawsone (2-hydroxy-1, 4-naphthoquinone) and its …

In the current era, an ever-emerging threat of multidrug-resistant (MDR) pathogens pose
serious health challenges to mankind. Researchers are uninterruptedly putting their efforts …

Abstract Naphthalene-1, 4-dione derivatives were synthesized and tested against selected
bacterial strains. All the tested compounds were prepared by direct introduction of …

Easy-to-synthesize aminoquinoline (AQ) appended naphthoquinone (NQ)-based
colorimetric and ratiometric probe (AQNQ) was successfully synthesized in one step with …

We report the discovery of marinoquinoline (3 H-pyrrolo [2, 3-c] quinoline) derivatives as
new chemotypes with antiplasmodial activity. We evaluated their inhibitory activities against …

One of the main hotspots in the global drug discovery endeavour is the microbial natural
products not only due to their great structural diversity and complexity, but also their capacity …

The Drug-induced liver injury is one of the common unfavourable impacts, which seriously
affects any drug therapy. This study documented the hepatoprotective efficacy of lawsone …