Pre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical
presentation is highly variable but hypertension and proteinuria are usually seen. These …

Placentation is a reproductive adaptation that permits fetal growth and development within
the protected confines of the female reproductive tract. Through this important role, the …

Background Childhood maltreatment is associated with adverse health outcomes and this
risk can be transmitted to the next generation. We aimed to investigate the association …

A number of prenatal experiences are associated with adverse outcomes after birth, ranging
from cardiovascular problems to psychiatric disease. Prenatal stress is associated with …

Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …

In brief Developmental programming refers to the long-term programming of gene
expression during fetal and postnatal development, resulting in altered organ function even …

Our efforts to understand the developmental origins of birth defects and disease have
primarily focused on maternal exposures and intrauterine stressors. Recently, research into …

The placenta is vital for mammalian development and a key determinant of life‐long health.
It is the interface between the mother and fetus and is responsible for transporting the …

In addition to their traditional role as immune sentinels, recent discoveries over the last
decade have shown that microglial functions now include regulation of neuronal/glial cell …

During pregnancy, conceptus-derived extravillous trophoblast (EVT) invades the
endomyometrium, anchors the placenta to the maternal uterus, and remodels the spiral …