L iver cell injury is a common occurrence in clinical practice. Indeed, measurements of
hepatocyte-derived serum transaminase levels are almost universally included in large …

Mitochondria are active in the continuous generation of reactive oxygen species (ROS),(eg,
superoxide), thereby favouring a situation of mitochondrial oxidative stress. Under oxidative …

Several new PLA2s have been identified based on their nucleotide gene sequences. They
were classified mainly into three groups: cytosolic PLA2 (cPLA2), secretary PLA2 (sPLA2) …

tert-Butyl hydroperoxide (TBHP) mobilizes arachidonic acid (AA) from membrane
phospholipids in rat hepatocytes under cytotoxic conditions, thus leading to an increase in …

Mammals possess various types of secretory phospholipase A 2, which differ in the primary
structure and tissue distribution. The phosholipase A 2 receptor (PLA 2 R) recognizes group …

It is essential to minimize damage to normal tissues during radiation therapy and many
strategies have been employed in finding the best methods for radioprotection. This book …

In response to oxidant stress, the cardiovascular system is known to express a number of
genes, which could occur owing to the participation of mitogen-activated protein kinases …

Although oxidants such as superoxide (O 2.-) and hydrogen peroxide (H 2 O 2) play a role in
host-mediated destruction of foreign pathogens yet excessive generation of oxidants may …

We have previously examined the ability of air pollution particles (PM10) to promote release
of the proinflammatory cytokine tumor necrosis factor-α (TNF-α) from human peripheral …

The intracellular events that lead to arachidonic acid release from bovine endothelial cells in
culture treated with hydrogen peroxide were characterized. The hydrogen peroxide …