Updates on systemic therapy for hepatocellular carcinoma

P Ntellas, I Chau - American Society of Clinical Oncology Educational …, 2024 - ascopubs.org
This review explores the dynamic landscape of hepatocellular carcinoma (HCC) treatment,
emphasizing on recent developments across various stages and therapeutic approaches …

The new era of systemic treatment for hepatocellular carcinoma: from the first line to the optimal sequence

M Cerreto, F Cardone, L Cerrito, L Stella… - Current …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) represents the most common primary liver cancer and is
considered a major global health problem as one of the leading causes of cancer-related …

Sorafenib vs. Lenvatinib in advanced hepatocellular carcinoma after atezolizumab/bevacizumab failure: A real-world study

YE Chon, DY Kim, MN Kim, BK Kim… - Clinical and …, 2024 - pmc.ncbi.nlm.nih.gov
Background/Aims Atezolizumab plus bevacizumab (ATE+ BEV) therapy has become the
recommended first-line therapy for patients with unresectable hepatocellular carcinoma …

Initial clinical experience with durvalumab plus tremelimumab in patients with unresectable hepatocellular carcinoma in real‑world practice

S Shimose, I Saeki, T Tomonari, T Ito… - Oncology …, 2024 - spandidos-publications.com
Although durvalumab plus tremelimumab (Dur/Tre) has been approved as first-line therapy
for patients with unresectable hepatocellular carcinoma (u-HCC), its outcomes in real-world …

The rapidly evolving landscape of HCC: Selecting the optimal systemic therapy

V Zanuso, L Rimassa, C Braconi - Hepatology, 2023 - journals.lww.com
Over the past years, there has been a remarkable advance in the systemic treatment options
for advanced HCC. The overall survival has gradually increased over time, with larger …

Improved clinical outcomes in advanced hepatocellular carcinoma treated with transarterial chemoembolization plus atezolizumab and bevacizumab: a bicentric …

F Cao, C Shi, G Zhang, J Luo, J Zheng, W Hao - BMC cancer, 2023 - Springer
Purpose The aim of the present study was to assess the efficacy and safety of transarterial
chemoembolization (TACE) combined with atezolizumab and bevacizumab (hereafter …

EASL Clinical Practice Guidelines on the management of hepatocellular carcinoma

B Sangro, J Argemi, M Ronot, V Paradis, T Meyer… - Journal of …, 2024 - Elsevier
Liver cancer is the third leading cause of cancer-related deaths worldwide, with
hepatocellular carcinoma (HCC) accounting for approximately 90% of primary liver cancers …

Evolution of Systemic Treatment for Hepatocellular Carcinoma: Changing Treatment Strategies and Concepts

M Moriguchi, S Kataoka, Y Itoh - Cancers, 2024 - mdpi.com
Simple Summary Systemic therapy for hepatocellular carcinoma has been advancing
rapidly. With the advent of drugs with high response rates and combination immunotherapy …

Treatment options for advanced hepatocellular carcinoma: the potential of biologics

F Rossari, S Foti, S Camera, M Persano… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Advanced hepatocellular carcinoma (HCC) represents a significant global
health burden, whose treatment has been recently revolutionized by the advent of biologic …

[HTML][HTML] Early Changes in Alpha-Fetoprotein and Des-γ-Carboxy Prothrombin Are Useful Predictors of Antitumor Response to Durvalumab Plus Tremelimumab …

T Kuzuya, N Kawabe, H Muto, Y Wada, G Komura… - Current …, 2024 - mdpi.com
The relationship between antitumor response and tumor marker changes was evaluated in
patients with advanced hepatocellular carcinoma treated with durvalumab plus …