[HTML][HTML] Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine

P Dhyani, C Quispe, E Sharma, A Bahukhandi… - Cancer cell …, 2022 - Springer
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …

Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021 - Wiley Online Library
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …

[HTML][HTML] Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

P Asgharian, AP Tazekand, K Hosseini… - Cancer cell …, 2022 - Springer
Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …

Natural coumarins: exploring the pharmacological complexity and underlying molecular mechanisms

J Sharifi-Rad, N Cruz-Martins… - Oxidative Medicine …, 2021 - Wiley Online Library
Coumarins belong to the benzopyrone family commonly found in many medicinal plants.
Natural coumarins demonstrated a wide spectrum of pharmacological activities, including …

[HTML][HTML] Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence

B Salehi, C Quispe, I Chamkhi, N El Omari… - Frontiers in …, 2021 - frontiersin.org
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

Diosgenin: an updated pharmacological review and therapeutic perspectives

P Semwal, S Painuli, T Abu-Izneid… - Oxidative medicine …, 2022 - Wiley Online Library
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

Purification, structure and biological activity of pumpkin polysaccharides: a review

X Ji, B Peng, H Ding, B Cui, H Nie… - Food Reviews …, 2023 - Taylor & Francis
The pumpkin has been used frequently as functional foods. Phytochemical and
pharmacological investigations have shown that polysaccharides derived from pumpkins …

[HTML][HTML] Cinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits

J Sharifi-Rad, A Dey, N Koirala, S Shaheen… - Frontiers in …, 2021 - frontiersin.org
The genus Cinnamomum includes a number of plant species largely used as food, food
additives and spices for a long time. Different traditional healing systems have used these …

[HTML][HTML] Diet, lifestyle and cardiovascular diseases: linking pathophysiology to cardioprotective effects of natural bioactive compounds

J Sharifi-Rad, CF Rodrigues, F Sharopov… - International journal of …, 2020 - mdpi.com
Heart and blood vessels disorders comprise one of the main causes of death worldwide.
Pharmacologically active natural compounds have been used as a complementary therapy …

[HTML][HTML] Probiotics: versatile bioactive components in promoting human health

J Sharifi-Rad, CF Rodrigues, Z Stojanović-Radić… - Medicina, 2020 - mdpi.com
The positive impact of probiotic strains on human health has become more evident than ever
before. Often delivered through food, dietary products, supplements, and drugs, different …