What is really dangerous: anaemia or transfusion?

A Shander, M Javidroozi, S Ozawa… - British journal of …, 2011 - academic.oup.com
While complex physiological mechanisms exist to regulate and optimize tissue oxygenation
under various conditions, clinical and experimental evidence indicates that anaemia …

Restrictive versus liberal transfusion strategy in the perioperative and acute care settings

F Hovaguimian, PS Myles - Anesthesiology, 2016 - ingentaconnect.com
Background: Blood transfusions are associated with morbidity and mortality. However,
restrictive thresholds could harm patients less able to tolerate anemia. Using a context …

Iron deficiency anemia—bridging the knowledge and practice gap

A Shander, LT Goodnough, M Javidroozi… - Transfusion medicine …, 2014 - Elsevier
Despite its high prevalence, anemia often does not receive proper clinical attention, and
detection, evaluation, and management of iron deficiency anemia and iron-restricted …

Timing of surgical antimicrobial prophylaxis: a phase 3 randomised controlled trial

WP Weber, E Mujagic, M Zwahlen, M Bundi… - The Lancet Infectious …, 2017 - thelancet.com
Background Based on observational studies, administration of surgical antimicrobial
prophylaxis (SAP) for the prevention of surgical site infection (SSI) is recommended within …

[HTML][HTML] Risk factors, short and long term outcome of anastomotic leaks in rectal cancer

O Jannasch, T Klinge, R Otto, C Chiapponi… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Background An anastomotic leak (AL) after colorectal surgery is one major reason for
postoperative morbidity and mortality. There is growing evidence that AL affects short and …

Postoperative abdominal wound infection–epidemiology, risk factors, identification, and management

SC Azoury, NE Farrow, QL Hu, KC Soares… - Chronic Wound Care …, 2015 - Taylor & Francis
Surgical site infections (SSIs) complicate the postoperative course of a significant proportion
of general abdominal surgical patients and are associated with excessive health care costs …

The Michigan experience with safety and effectiveness of tranexamic acid use in hip and knee arthroplasty

B Hallstrom, B Singal, ME Cowen, KC Roberts… - JBJS, 2016 - journals.lww.com
Background: The efficacy of tranexamic acid (TXA) in reducing blood loss and transfusion
requirements in total hip and knee arthroplasty has been well established in small controlled …

Anaemia in the older surgical patient: a review of prevalence, causes, implications and management

J Partridge, D Harari, J Gossage… - Journal of the Royal …, 2013 - journals.sagepub.com
This review provides the clinician with a summary of the causes, implications and potential
treatments for the management of anaemia in the older surgical patient. The prevalence of …

Serum proteomics of active tuberculosis patients and contacts reveals unique processes activated during Mycobacterium tuberculosis infection

J Mateos, O Estévez, Á González-Fernández… - Scientific Reports, 2020 - nature.com
Tuberculosis (TB) is the most lethal infection among infectious diseases. The specific aim of
this study was to establish panels of serum protein biomarkers representative of active TB …

Risk factor analysis and microbial etiology of surgical site infections following lower segment caesarean section

D De, S Saxena, G Mehta, R Yadav… - International Journal of …, 2013 - Wiley Online Library
Background. Lower segment caesarean section (LSCS) is a common mode of delivery now
and surgical site infection is the second most common infectious complication in these …