Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

Biomimetic and bio‐inspired membranes draw great attention and generate extensive efforts
to solve environmental, health, and energy issues. In this field, track‐etched membranes …

In two decades, the solid state and polymer nanopores became attractive method for the
protein sensing with high specificity and sensitivity. They also allow the characterization of …

Tauopathies are a heterogenous family of progressive neurodegenerative diseases defined
by the appearance of proteinaceous lesions within the brain composed of abnormally folded …

Soluble oligomers of amyloid-forming proteins are implicated as toxic species in the context
of several neurodegenerative diseases. Since the size and shape of these oligomers …

The accumulation of hyperphosphorylated fibrillar Tau aggregates in the brain is one of the
defining hallmarks of Tauopathy diseases, including Alzheimer's disease. However, the …

Several neurodegenerative diseases have been linked to proteins or peptides that are
prone to aggregate in different brain regions. Aggregation of amyloid-β (Aβ) peptides is …

The aggregation of tau into insoluble fibrils is a defining feature of neurodegenerative
tauopathies. However, tau has a positive overall charge and is highly soluble; so …

In this work, early-stage Aβ42 aggregates were detected using a real-time fast amyloid
seeding and translocation (RT-FAST) assay. Specifically, Aβ42 monomers were incubated …

Protein detection and identification at the single-molecule level are major challenges in
many biotechnological fields. Solid-state nanopores have raised attention as label-free …