A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Abstract Development of a highly effective vaccine or antibodies for the prevention and
ultimately elimination of malaria is urgently needed. Here we report the isolation of a number …
ultimately elimination of malaria is urgently needed. Here we report the isolation of a number …
Force spectroscopy of the Plasmodium falciparum vaccine candidate circumsporozoite protein suggests a mechanically pliable repeat region
AP Patra, S Sharma, SRK Ainavarapu - Journal of Biological Chemistry, 2017 - ASBMB
The most effective vaccine candidate of malaria is based on the Plasmodium falciparum
circumsporozoite protein (CSP), a major surface protein implicated in the structural strength …
circumsporozoite protein (CSP), a major surface protein implicated in the structural strength …
Substrate-imprinted docking of Agrobacterium tumefaciens uronate dehydrogenase for increased substrate selectivity
A Murugan, R Prathiviraj, D Mothay… - International journal of …, 2019 - Elsevier
Agrobacterium tumefaciens uronate dehydrogenase (AtuUdh) belongs to the short-chain
dehydrogenase superfamily, specifically those acting on the CH-OH group of donor with …
dehydrogenase superfamily, specifically those acting on the CH-OH group of donor with …
Molecular Evolutionary Constraints that Determine the Avirulence State of Clostridium botulinum C2 Toxin
Clostridium botulinum (group-III) is an anaerobic bacterium producing C2 toxin along with
botulinum neurotoxins. C2 toxin is belonged to binary toxin A family in bacterial ADP …
botulinum neurotoxins. C2 toxin is belonged to binary toxin A family in bacterial ADP …
Structural constraints-based evaluation of immunogenic avirulent toxins from Clostridium botulinum C2 and C3 toxins as subunit vaccines
A Prisilla, R Prathiviraj, R Sasikala… - Infection, Genetics and …, 2016 - Elsevier
Clostridium botulinum (group-III) is an anaerobic bacterium producing C2 and C3 toxins in
addition to botulinum neurotoxins in avian and mammalian cells. C2 and C3 toxins are …
addition to botulinum neurotoxins in avian and mammalian cells. C2 and C3 toxins are …
Chelation of Ca2+ ions by a peptide from the repeat region of the Plasmodium falciparum circumsporozoite protein
E Topchiy, T Lehmann - Malaria Journal, 2014 - Springer
Background Elegant efforts towards the determination of the structural tendencies of
peptides derived from the Plasmodium falciparum circumsporozoite protein allowed the …
peptides derived from the Plasmodium falciparum circumsporozoite protein allowed the …