The modification of proteins by the addition of ubiquitin and other ubiquitin-like proteins
(UBLs) is involved in a wide range of cellular processes including cell cycle progression, the …

Post-translational protein regulation allows for fine-tuning of cellular functions and involves a
wide range of modifications, including ubiquitin and ubiquitin-like modifiers (Ubls). The …

Post-translational modifications (PTMs) are fundamental to essential biological processes,
exerting significant influence over gene expression, protein localization, stability, and …

Aberrant SUMOylation contributes to the progression of hepatocellular carcinoma (HCC), yet
the molecular mechanisms have not been well elucidated. RING-type E3 ubiquitin ligase …

Sumoylation is a post-translation modification (PTM) mechanism that involves many critical
biological processes, such as gene expression, localizing and stabilizing proteins, and …

SUMOylation is an essential post-translational modification system with the ability to
regulate nearly all aspects of cellular physiology. Three major paralogues SUMO1, SUMO2 …

Lysine SUMOylation plays an essential role in various biological functions. Several
approaches integrating various algorithms have been developed for predicting SUMOylation …

Metabolic dysfunction-associated steatotic liver disease [MASLD] is a pervasive
multifactorial health burden. Post-translational modifications [PTMs] of amino acid residues …

Posttranslational modification (PTM) is an important biological mechanism to promote
functional diversity among the proteins. So far, a wide range of PTMs has been identified …

Sumoylation is a reversible post-translational modification that regulates certain significant
biochemical functions in proteins. The protein alterations caused by sumoylation are …