Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …

In calcium imaging studies, Ca2+ transients are commonly interpreted as neuronal action
potentials (APs). However, our findings demonstrate that robust optical Ca2+ transients …

Neurodevelopmental disorders (NDDs) affect 4.7% of the global population and are
associated with delays in brain development and a spectrum of impairments that can lead to …

Economic efficiency has been a popular explanation for how networks self-organize within
the developing nervous system. However, the precise nature of the economic negotiations …

Biological membrane potentials, or voltages, are a central facet of cellular life. Optical
methods to visualize cellular membrane voltages with fluorescent indicators are an attractive …

Magnetogenetics was developed to remotely control genetically targeted neurons. A variant
of magnetogenetics uses magnetic fields to activate transient receptor potential vanilloid …

The development of fluorescent dyes that emit and absorb light at wavelengths greater than
700 nm and that respond to biochemical and biophysical events in living systems remains …

Voltage imaging and “all-optical electrophysiology” in human induced pluripotent stem cell
(hiPSC)-derived neurons have opened unprecedented opportunities for high-throughput …

Many controlled in vitro studies have demonstrated how postsynaptic responses to
presynaptic spikes are not constant but depend on short-term synaptic plasticity (STP) and …

Magnetogenetics promises remote control of neurons, but its validity is questioned due to
controversies surrounding the underlying mechanisms and deficits in reproducibility. Recent …